HitPredict - High confidence protein-protein interactions

Interactor 1: CLM8 (Q9UGN4)
CMRF35-like molecule 8 (CLM-8) (CD300 antigen-like family member A) (CMRF-35-H9) (CMRF35-H9) (CMRF35-H) (IRC1/IRC2) (Immunoglobulin superfamily member 12) (IgSF12) (Inhibitory receptor protein 60) (IRp60) (NK inhibitory receptor) (CD antigen CD300a)
Gene: CD300A

Interactor 2: CLM8 (Q9UGN4)
CMRF35-like molecule 8 (CLM-8) (CD300 antigen-like family member A) (CMRF-35-H9) (CMRF35-H9) (CMRF35-H) (IRC1/IRC2) (Immunoglobulin superfamily member 12) (IgSF12) (Inhibitory receptor protein 60) (IRp60) (NK inhibitory receptor) (CD antigen CD300a)
Gene: CD300A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20959446
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	V-set~V-set
Common GO terms	GO:0001786 - phosphatidylserine binding GO:0002376 - immune system process GO:0004888 - transmembrane signaling receptor activity GO:0005886 - plasma membrane GO:0007155 - cell adhesion and 21 others more... GO:0008429 - phosphatidylethanolamine binding GO:0016020 - membrane GO:0030889 - negative regulation of B cell proliferation GO:0032516 - positive regulation of phosphoprotein phosphatase activity GO:0033007 - negative regulation of mast cell activation involved in immune response GO:0034125 - negative regulation of MyD88-dependent toll-like receptor signaling pathway GO:0038023 - signaling receptor activity GO:0043305 - negative regulation of mast cell degranulation GO:0043407 - negative regulation of MAP kinase activity GO:0048147 - negative regulation of fibroblast proliferation GO:0050856 - regulation of T cell receptor signaling pathway GO:0050859 - negative regulation of B cell receptor signaling pathway GO:0051134 - negative regulation of NK T cell activation GO:0060101 - negative regulation of phagocytosis, engulfment GO:0070062 - extracellular exosome GO:0070821 - tertiary granule membrane GO:0101003 - ficolin-1-rich granule membrane GO:1902564 - negative regulation of neutrophil activation GO:1902567 - negative regulation of eosinophil activation GO:1902569 - negative regulation of activation of Janus kinase activity GO:2000417 - negative regulation of eosinophil migration
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1	299
Hs

1	299

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Last updated: 15 Jul 2024