Interactor 1: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Interactor 2: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 15331633
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HECT~HECT, RCC1~RCC1
Common GO terms GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000209 - protein polyubiquitination
GO:0003723 - RNA binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
and 11 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

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Last updated: 15 Jul 2024