HitPredict

Interactor 1: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Interactor 2: ICAM5 (Q9UMF0)
Intercellular adhesion molecule 5 (ICAM-5) (Telencephalin)
Gene: ICAM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 296 Hs			1 924
+	Hs
		1344610 FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81		ICAM5_HUMAN (1-924): 1.33e-162: 501: 100.00
+	Hs
		1018314 FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00		CNTN1_HUMAN (12-778): 1.4e-52: 201: 11.81
+	Hs
		1356264 FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00		ROBO1_HUMAN (8-393): 4.28e-30: 131: 9.25
+	Hs
		1268546 FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00		PXDN_HUMAN (39-402): 5.53e-18: 91.8: 15.86
+	Hs
		400122 FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81		ICAM1_HUMAN (121-572): 8.18e-25: 111: 18.93
+	Hs
		685328 FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00		L1CAM_HUMAN (505-783): 9.61e-12: 71.2: 27.62
+	Hs
		957568 FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00		PGBM_HUMAN (119-256): 2.86e-09: 63.5: 14.49
+	Hs
		1268542 FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81		PXDN_HUMAN (39-402): 5.53e-18: 91.8: 15.86
+	Hs
		1059133 FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81		ICAM4_HUMAN (33-235): 4.82e-16: 81.3: 34.14
+	Hs
		685320 FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81		L1CAM_HUMAN (505-783): 9.61e-12: 71.2: 27.62
+	Hs
		957565 FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81		PGBM_HUMAN (119-256): 2.86e-09: 63.5: 14.49