Interactor 1: POLI (Q9UNA4)
DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B)
Gene: POLI

Interactor 2: POLH (Q9Y253)
DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein)
Gene: POLH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 12606586, 23248005
Identification Methods two hybrid, far western blotting, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IMS~IMS, IMS~IMS_C, IMS_C~IMS_C
Common GO terms GO:0003684 - damaged DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0006281 - DNA repair
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 740
Hs

1 713
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Sp
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024