Protein: SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (BAF60C)

Gene: SMRD3, SMARCD3
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q6STE5

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001221 - transcription coregulator binding
GO:0002052 - positive regulation of neuroblast proliferation
GO:0003139 - secondary heart field specification
GO:0003219 - cardiac right ventricle formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1247660

SMRC2
SWI/SNF complex subunit SMARCC2

7

19

Small-scale

0.960

High

1247671

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

5

5

High-throughput

0.927

High

910951

IMA1
Importin subunit alpha-1

2

6

High-throughput

0.789

High

1247670

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

8

8

Small-scale

0.749

High

154711

ARI1A
AT-rich interactive domain-containing protein 1A

8

12

Small-scale

0.746

High

903397

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

8

20

Small-scale

0.745

High

1247668

SMRC1
SWI/SNF complex subunit SMARCC1

2

18

Small-scale

0.737

High

1247669

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

2

5

Small-scale

0.737

High

1247666

DPF3
Zinc finger protein DPF3

6

16

Small-scale

0.729

High

1086615

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

5

6

Small-scale

0.706

High

1247667

REQU
Zinc finger protein ubi-d4

4

16

High-throughput

0.699

High

1149729

SSXT
Protein SSXT

4

20

High-throughput

0.694

High

911278

IMA5
Importin subunit alpha-5

1

6

High-throughput

0.691

High

1196879

BCL7A
B-cell CLL/lymphoma 7 protein family member A

4

9

High-throughput

0.691

High

1247663

BCL7C
B-cell CLL/lymphoma 7 protein family member C

3

9

High-throughput

0.675

High

903186

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

4

20

Small-scale

0.672

High

1247684

NUP50
Nuclear pore complex protein Nup50

3

3

High-throughput

0.667

High

1247659

ARI1B
AT-rich interactive domain-containing protein 1B

3

15

Small-scale

0.650

High

1030004

RELB
Transcription factor RelB

2

6

High-throughput

0.628

High

1247665

DPF1
Zinc finger protein neuro-d4

2

16

High-throughput

0.611

High

581674

MYOD1
Myoblast determination protein 1

2

4

Small-scale

0.584

High

1247680

BRD7
Bromodomain-containing protein 7

2

15

High-throughput

0.584

High

1247654

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

5

Small-scale

0.575

High

355236

ACL6A
Actin-like protein 6A

2

16

Small-scale

0.571

High

1247656

PB1
Protein polybromo-1

2

20

Small-scale

0.571

High

789516

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.552

High

132110

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.536

High

1247674

THAP7
THAP domain-containing protein 7

1

1

High-throughput

0.536

High

396356

ESR1
Estrogen receptor

1

20

Small-scale

0.501

High

430051

JUN
Transcription factor Jun

1

4

Small-scale

0.501

High

520597

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.501

High

533226

RARB
Retinoic acid receptor beta

1

20

Small-scale

0.501

High

543580

ERR1
Steroid hormone receptor ERR1

1

20

Small-scale

0.501

High

565525

RARG
Retinoic acid receptor gamma

1

19

Small-scale

0.501

High

625830

RXRA
Retinoic acid receptor RXR-alpha

1

18

Small-scale

0.501

High

771005

RORA
Nuclear receptor ROR-alpha

1

15

Small-scale

0.501

High

787876

SRBP1
Sterol regulatory element-binding protein 1

1

6

Small-scale

0.501

High

823846

PBX1
Pre-B-cell leukemia transcription factor 1

1

4

Small-scale

0.501

High

1247672

NR1H4
Bile acid receptor

1

20

Small-scale

0.501

High

1247682

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

11

Small-scale

0.500

High

1247664

F168A
Protein FAM168A

1

2

High-throughput

0.489

High

1247676

TX13B
Testis-expressed protein 13B

1

3

High-throughput

0.489

High

1247683

S18L2
SS18-like protein 2

1

12

High-throughput

0.489

High

1158121

MK14
Mitogen-activated protein kinase 14

1

0

Small-scale

0.480

High

143062

NFIB
Nuclear factor 1 B-type

1

11

High-throughput

0.479

High

210030

CRX
Cone-rod homeobox protein

1

17

High-throughput

0.479

High

274013

CREST
Calcium-responsive transactivator

1

20

High-throughput

0.479

High

370700

FOS
Protein c-Fos

1

5

High-throughput

0.479

High

372351

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

474073

NFIC
Nuclear factor 1 C-type

1

13

High-throughput

0.479

High

533945

IRF1
Interferon regulatory factor 1

1

3

High-throughput

0.479

High

538419

EGR2
E3 SUMO-protein ligase EGR2

1

1

High-throughput

0.479

High

540893

ERG
Transcriptional regulator ERG

1

12

High-throughput

0.479

High

577453

ETS1
Protein C-ets-1

1

12

High-throughput

0.479

High

652531

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

Small-scale

0.479

High

662239

PAX7
Paired box protein Pax-7

1

11

High-throughput

0.479

High

685239

PAX6
Paired box protein Pax-6

1

9

High-throughput

0.479

High

703158

TEAD1
Transcriptional enhancer factor TEF-1

1

3

High-throughput

0.479

High

775437

DDIT3
DNA damage-inducible transcript 3 protein

1

2

Small-scale

0.479

High

775867

HNF1B
Hepatocyte nuclear factor 1-beta

1

12

High-throughput

0.479

High

833973

HNF4A
Hepatocyte nuclear factor 4-alpha

1

18

High-throughput

0.479

High

877524

LHX1
LIM/homeobox protein Lhx1

1

12

High-throughput

0.479

High

904851

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

987716

GRB2
Growth factor receptor-bound protein 2

1

3

High-throughput

0.479

High

995651

ACTC
Actin, alpha cardiac muscle 1

1

8

High-throughput

0.479

High

1030962

FLI1
Friend leukemia integration 1 transcription factor

1

12

Small-scale

0.479

High

1087814

NFIA
Nuclear factor 1 A-type

1

12

High-throughput

0.479

High

1129629

MDC1
Mediator of DNA damage checkpoint protein 1

1

7

High-throughput

0.479

High

1133479

NFIX
Nuclear factor 1 X-type

1

12

High-throughput

0.479

High

1228243

ARID2
AT-rich interactive domain-containing protein 2

1

14

High-throughput

0.479

High

1247655

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1247657

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

1247658

S11IP
Serine/threonine-protein kinase 11-interacting protein

1

2

High-throughput

0.479

High

1247661

SP7
Transcription factor Sp7

1

3

High-throughput

0.479

High

1247662

PHF10
PHD finger protein 10

1

17

High-throughput

0.479

High

1247673

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

9

High-throughput

0.479

High

1247677

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1247678

BRD9
Bromodomain-containing protein 9

1

18

High-throughput

0.479

High

1247681

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

11

High-throughput

0.479

High

1247685

STA13
StAR-related lipid transfer protein 13

1

1

Small-scale

0.464

High

1247675

B2L13
Bcl-2-like protein 13

1

0

Small-scale

0.460

High

179363

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.458

High

952906

ACTB
Actin, cytoplasmic 1

1

9

Small-scale

0.445

High

1247679

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.445

High

1141705

EEA1
Early endosome antigen 1

1

1

High-throughput

0.437

High

387122

TNNC2
Troponin C, skeletal muscle

1

0

High-throughput

0.279

Low

1129063

RASA3
Ras GTPase-activating protein 3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025