Protein: SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (60 kDa BRG-1/Brm-associated factor subunit B) (BRG1-associated factor 60B) (BAF60B)

Gene: SMRD2, SMARCD2
Organism: Homo sapiens
Interactions: 170
UniProt ID: Q92925

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1347518

SMRC2
SWI/SNF complex subunit SMARCC2

7

20

High-throughput

0.962

High

1370738

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

6

5

High-throughput

0.940

High

911333

IMA5
Importin subunit alpha-5

3

6

High-throughput

0.839

High

1370681

SMRC1
SWI/SNF complex subunit SMARCC1

2

20

High-throughput

0.811

High

911034

IMA1
Importin subunit alpha-1

2

6

High-throughput

0.776

High

154736

ARI1A
AT-rich interactive domain-containing protein 1A

10

15

Small-scale

0.753

High

1370736

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

7

9

High-throughput

0.747

High

903446

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

7

20

Small-scale

0.739

High

1247669

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

2

5

Small-scale

0.737

High

1368345

REQU
Zinc finger protein ubi-d4

6

20

High-throughput

0.736

High

1086665

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

6

6

Small-scale

0.734

High

1368322

DPF3
Zinc finger protein DPF3

6

20

Small-scale

0.729

High

1149744

SSXT
Protein SSXT

5

20

High-throughput

0.718

High

1196899

BCL7A
B-cell CLL/lymphoma 7 protein family member A

5

9

High-throughput

0.716

High

1338747

ARI1B
AT-rich interactive domain-containing protein 1B

5

19

High-throughput

0.709

High

1370768

NUP50
Nuclear pore complex protein Nup50

4

3

High-throughput

0.691

High

903223

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

4

20

Small-scale

0.686

High

1228266

ARID2
AT-rich interactive domain-containing protein 2

4

17

High-throughput

0.676

High

1357460

BCL7C
B-cell CLL/lymphoma 7 protein family member C

3

9

High-throughput

0.675

High

1030021

RELB
Transcription factor RelB

3

7

High-throughput

0.667

High

1113905

CUL3
Cullin-3

3

1

High-throughput

0.656

High

520256

ANDR
Androgen receptor

3

20

Small-scale

0.640

High

1356495

PHF10
PHD finger protein 10

2

20

High-throughput

0.628

High

414344

P53
Cellular tumor antigen p53

1

6

High-throughput

0.618

High

132205

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

3

High-throughput

0.611

High

355268

ACL6A
Actin-like protein 6A

2

16

High-throughput

0.611

High

1368263

DPF1
Zinc finger protein neuro-d4

2

20

High-throughput

0.611

High

1370756

BRD7
Bromodomain-containing protein 7

2

17

High-throughput

0.611

High

143165

NFIB
Nuclear factor 1 B-type

2

15

High-throughput

0.584

High

242490

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

260259

BRD4
Bromodomain-containing protein 4

2

20

High-throughput

0.584

High

372752

MYC
Myc proto-oncogene protein

2

7

High-throughput

0.584

High

474178

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

674281

BRD2
Bromodomain-containing protein 2

2

20

High-throughput

0.584

High

1087915

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

1104631

IKZF1
DNA-binding protein Ikaros

2

4

Small-scale

0.584

High

1133578

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

1370766

IKZF3
Zinc finger protein Aiolos

2

3

Small-scale

0.584

High

1370747

TX13A
Testis-expressed protein 13A

2

3

High-throughput

0.574

High

401244

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

3

High-throughput

0.571

High

1144786

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

2

1

High-throughput

0.558

High

1370753

UNKL
Putative E3 ubiquitin-protein ligase UNKL

1

0

Small-scale

0.549

High

1370765

S18L2
SS18-like protein 2

2

12

High-throughput

0.549

High

1143455

PCM1
Pericentriolar material 1 protein

2

0

High-throughput

0.547

High

854203

KI67
Proliferation marker protein Ki-67

1

5

High-throughput

0.536

High

953011

ACTB
Actin, cytoplasmic 1

1

9

High-throughput

0.536

High

986615

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.536

High

993282

ACTG
Actin, cytoplasmic 2

1

9

High-throughput

0.536

High

1163116

H2B2E
Histone H2B type 2-E

1

18

High-throughput

0.536

High

1278781

HDGR2
Hepatoma-derived growth factor-related protein 2

1

1

High-throughput

0.536

High

995744

ACTC
Actin, alpha cardiac muscle 1

2

8

High-throughput

0.533

High

887081

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.527

High

287464

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.513

High

185902

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

1370761

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

11

Small-scale

0.500

High

1364803

F168A
Protein FAM168A

1

2

High-throughput

0.489

High

1370746

TX13B
Testis-expressed protein 13B

1

3

High-throughput

0.489

High

1316427

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.486

High

181549

TBXT
T-box transcription factor T

1

10

High-throughput

0.479

High

186782

P73
Tumor protein p73

1

6

High-throughput

0.479

High

210078

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

216977

KLF4
Krueppel-like factor 4

1

10

High-throughput

0.479

High

274039

CREST
Calcium-responsive transactivator

1

20

High-throughput

0.479

High

277764

H2AY
Core histone macro-H2A.1

1

8

High-throughput

0.479

High

340923

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

9

High-throughput

0.479

High

370746

FOS
Protein c-Fos

1

6

High-throughput

0.479

High

396654

ESR1
Estrogen receptor

1

20

High-throughput

0.479

High

406460

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

412384

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

502082

H2AZ
Histone H2A.Z

1

4

High-throughput

0.479

High

533961

IRF1
Interferon regulatory factor 1

1

5

High-throughput

0.479

High

540923

ERG
Transcriptional regulator ERG

1

18

High-throughput

0.479

High

577482

ETS1
Protein C-ets-1

1

18

High-throughput

0.479

High

581708

MYOD1
Myoblast determination protein 1

1

5

High-throughput

0.479

High

589324

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

591765

H2AX
Histone H2AX

1

8

High-throughput

0.479

High

606976

CEBPB
CCAAT/enhancer-binding protein beta

1

10

High-throughput

0.479

High

611271

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

652557

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

Small-scale

0.479

High

662261

PAX7
Paired box protein Pax-7

1

17

High-throughput

0.479

High

662477

GATA2
Endothelial transcription factor GATA-2

1

10

High-throughput

0.479

High

662626

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

10

High-throughput

0.479

High

685294

PAX6
Paired box protein Pax-6

1

14

High-throughput

0.479

High

696119

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

703181

TEAD1
Transcriptional enhancer factor TEF-1

1

4

High-throughput

0.479

High

725300

TLX1
T-cell leukemia homeobox protein 1

1

7

High-throughput

0.479

High

765767

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.479

High

768808

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

775456

DDIT3
DNA damage-inducible transcript 3 protein

1

2

Small-scale

0.479

High

834015

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

846928

ETV4
ETS translocation variant 4

1

20

High-throughput

0.479

High

851630

GATA4
Transcription factor GATA-4

1

11

High-throughput

0.479

High

872604

SOX2
Transcription factor SOX-2

1

15

High-throughput

0.479

High

873113

SOX9
Transcription factor SOX-9

1

17

High-throughput

0.479

High

877540

LHX1
LIM/homeobox protein Lhx1

1

17

High-throughput

0.479

High

879330

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

13

High-throughput

0.479

High

883300

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.479

High

890381

NU153
Nuclear pore complex protein Nup153

1

8

High-throughput

0.479

High

895770

LHX2
LIM/homeobox protein Lhx2

1

18

High-throughput

0.479

High

938488

PAX9
Paired box protein Pax-9

1

14

High-throughput

0.479

High

946178

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.479

High

987820

GRB2
Growth factor receptor-bound protein 2

1

5

High-throughput

0.479

High

1017081

H33
Histone H3.3

1

7

High-throughput

0.479

High

1030973

FLI1
Friend leukemia integration 1 transcription factor

1

18

Small-scale

0.479

High

1054757

SUH
Recombining binding protein suppressor of hairless

1

2

High-throughput

0.479

High

1056637

PAX8
Paired box protein Pax-8

1

14

High-throughput

0.479

High

1088946

TP53B
TP53-binding protein 1

1

6

High-throughput

0.479

High

1091134

FOXC1
Forkhead box protein C1

1

5

High-throughput

0.479

High

1091239

FOXI1
Forkhead box protein I1

1

5

High-throughput

0.479

High

1098080

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.479

High

1100192

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

1106025

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

4

High-throughput

0.479

High

1106365

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

8

High-throughput

0.479

High

1118750

KLF5
Krueppel-like factor 5

1

11

High-throughput

0.479

High

1120268

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

1

Small-scale

0.479

High

1137436

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.479

High

1141249

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

1153569

MLF2
Myeloid leukemia factor 2

1

1

High-throughput

0.479

High

1153859

SMAD2
Mothers against decapentaplegic homolog 2

1

5

Small-scale

0.479

High

1155625

EZH2
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.479

High

1160880

TBR1
T-box brain protein 1

1

10

High-throughput

0.479

High

1229365

LHX8
LIM/homeobox protein Lhx8

1

18

High-throughput

0.479

High

1276586

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1287969

PB1
Protein polybromo-1

1

20

High-throughput

0.479

High

1329793

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1346873

SNIP1
Smad nuclear-interacting protein 1

1

1

Small-scale

0.479

High

1351111

SP7
Transcription factor Sp7

1

7

High-throughput

0.479

High

1366944

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1370735

LHX4
LIM/homeobox protein Lhx4

1

18

High-throughput

0.479

High

1370740

RING2
E3 ubiquitin-protein ligase RING2

1

5

High-throughput

0.479

High

1370741

FEV
Protein FEV

1

18

High-throughput

0.479

High

1370742

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1370743

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

9

High-throughput

0.479

High

1370744

SOX7
Transcription factor SOX-7

1

19

High-throughput

0.479

High

1370745

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.479

High

1370748

P63
Tumor protein 63

1

6

High-throughput

0.479

High

1370749

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

20

High-throughput

0.479

High

1370751

SOX17
Transcription factor SOX-17

1

18

High-throughput

0.479

High

1370752

BRD9
Bromodomain-containing protein 9

1

20

High-throughput

0.479

High

1370755

GCM1
Chorion-specific transcription factor GCMa

1

2

High-throughput

0.479

High

1370760

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

14

High-throughput

0.479

High

1370762

LHX3
LIM/homeobox protein Lhx3

1

16

High-throughput

0.479

High

1370764

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1370767

ELF5
ETS-related transcription factor Elf-5

1

20

High-throughput

0.479

High

1370769

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

High-throughput

0.479

High

1370770

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

1

High-throughput

0.479

High

187543

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.458

High

315837

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

1130135

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.458

High

1135761

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

Small-scale

0.458

High

1370754

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1370757

ANLN
Anillin

1

0

High-throughput

0.458

High

430199

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

799360

BRCA1
Breast cancer type 1 susceptibility protein

1

3

Small-scale

0.445

High

1199629

KLH22
Kelch-like protein 22

1

1

High-throughput

0.445

High

1239644

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

1

Small-scale

0.445

High

1370758

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.445

High

1277344

NT2NA
Notch homolog 2 N-terminal-like protein A

1

2

High-throughput

0.439

High

157702

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

346149

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.437

High

1323501

S11IP
Serine/threonine-protein kinase 11-interacting protein

1

2

High-throughput

0.437

High

1370750

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

284596

ECI2
Enoyl-CoA delta isomerase 2

1

4

High-throughput

0.407

High

1092609

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

4

High-throughput

0.407

High

975164

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.279

Low

347221

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.249

Low

1370737

Q96BE0
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

1370759

ITSN2
Intersectin-2

1

0

High-throughput

0.249

Low

1370739

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low

1370763

SL9A2
Sodium/hydrogen exchanger 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025