HitPredict

Interactor 1: P3C2B (O00750)
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.137) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta)
Gene: PIK3C2B

Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17474147
Identification Methods peptide array
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~SH2, PI3K_P85_iSH2~PI3_PI4_kinase, PI3_PI4_kinase~SH2, PI3K_C2~PI3K_P85_iSH2, PI3K_C2~SH2, PI3K_P85_iSH2~PI3Ka, PI3Ka~SH2
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005942 - phosphatidylinositol 3-kinase complex
GO:0043491 - phosphatidylinositol 3-kinase/protein kinase B signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1634
Hs

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Last updated: 15 Jul 2024