HitPredict

Interactor 1: SIM3 (Q9USQ4)
NASP-related protein sim3 (CENP-A escort protein sim3) (Silencing in the middle of the centromere protein 3)
Gene: SIM3

Interactor 2: CENPA (Q9Y812)
Histone H3-like centromeric protein cnp1 (Centromere protein 1) (CENP-A homolog) (CENPA homolog) (Silencing in the middle of the centromere protein 2)
Gene: cnp1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	18158900, 29194511
Identification Methods	affinity chromatography technology, pull down, unspecified method, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0034080 - CENP-A containing chromatin assembly
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 396 Sp			1 120
+	Sp
		457188 SIM3_SCHPO (1-389): 4.05e-115: 343: 100.00		H31_SCHPO (2-119): 1.36e-44: 143: 59.32
+	Hs
		825812 NASP_HUMAN (61-395): 1.18e-57: 202: 23.18		H31_HUMAN (2-119): 1.57e-47: 150: 61.86
+	Hs
		825814 NASP_HUMAN (61-395): 1.18e-57: 202: 23.18		H33_HUMAN (2-119): 9.88e-47: 148: 61.02
+	Hs
		825835 NASP_HUMAN (61-395): 1.18e-57: 202: 23.18		H31T_HUMAN (1-119): 9.46e-47: 148: 58.82
+	Hs
		825843 NASP_HUMAN (61-395): 1.18e-57: 202: 23.18		H32_HUMAN (2-119): 1.14e-46: 148: 61.86
+	Hs
		825838 NASP_HUMAN (61-395): 1.18e-57: 202: 23.18		H3C_HUMAN (2-119): 2.82e-45: 144: 60.17
+	Hs
		825837 NASP_HUMAN (61-395): 1.18e-57: 202: 23.18		H37_HUMAN (2-119): 1.5e-44: 143: 61.02
+	Mm
		69829 B1AU75_MOUSE (52-395): 1.18e-47: 175: 20.16		H31_MOUSE (2-119): 1.57e-47: 150: 61.86
+	Mm
		69830 B1AU75_MOUSE (52-395): 1.18e-47: 175: 20.16		H32_MOUSE (2-119): 1.14e-46: 148: 61.86
+	Mm
		69831 B1AU75_MOUSE (52-395): 1.18e-47: 175: 20.16		H33_MOUSE (2-119): 9.88e-47: 148: 61.02