HitPredict

Interactor 1: SEC13 (Q9V3J4)
Protein SEC13 homolog (GATOR complex protein SEC13) (Secretory protein 13)
Gene: SEC13

Interactor 2: MIO (Q9VQ89)
GATOR2 complex protein MIOS (Missing oocyte protein)
Gene: MIO

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27166823
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032008 - positive regulation of TOR signaling GO:0035859 - Seh1-associated complex GO:0061700 - GATOR2 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Dm			1 867
+	Dm
		1179397 SEH1_DROME (5-316): 9.88e-96: 290: 26.10		MIO_DROME (1-867): 0: 753: 100.00
+	Hs
		1289602 SEH1_HUMAN (4-346): 3.09e-74: 235: 26.06		MIOS_HUMAN (1-858): 0: 628: 30.87
+	Sc
		745405 SEC13_YEAST (8-297): 1.01e-74: 234: 47.46		SEA4_YEAST (89-852): 6.6e-142: 448: 21.20
+	Dm
		1179394 SEH1_DROME (5-316): 9.88e-96: 290: 26.10		Q86BR7_DROME (1-850): 2.94e-72: 255: 13.84
+	Dm
		1179399 SEH1_DROME (5-316): 9.88e-96: 290: 26.10		WDR24_DROME (1-850): 1.72e-72: 255: 13.61
+	Hs
		1289586 SEH1_HUMAN (4-346): 3.09e-74: 235: 26.06		WDR24_HUMAN (664-852): 4.56e-40: 161: 24.74
+	Dm
		52415 SEC13_DROME (1-345): 1.04e-83: 259: 100.00		A1Z7J7_DROME (2-225): 3.76e-20: 98.4: 11.02
+	Sp
		142026 SEC13_SCHPO (5-303): 5.41e-77: 240: 46.54		SEC31_SCHPO (2-255): 8.68e-18: 90.7: 12.59
+	Hs
		903431 SEH1_HUMAN (4-346): 3.09e-74: 235: 26.06		WDR5_HUMAN (222-464): 4.86e-19: 91.5: 8.00
+	Hs
		1162291 SEH1_HUMAN (4-346): 3.09e-74: 235: 26.06		WDR59_HUMAN (62-303): 1.21e-12: 74.1: 14.46
+	Hs
		1281491 FBXW7_HUMAN (1-329): 3.19e-61: 210: 14.72		WDR37_HUMAN (43-267): 4.17e-20: 96.5: 17.30
+	Hs
		903418 FBXW7_HUMAN (1-329): 3.19e-61: 210: 14.72		WDR5_HUMAN (222-464): 4.86e-19: 91.5: 8.00
+	Hs
		903077 WDR5_HUMAN (42-354): 1.87e-63: 206: 16.51		WDR5_HUMAN (222-464): 4.86e-19: 91.5: 8.00
+	Hs
		1083339 FBXW7_HUMAN (1-329): 3.19e-61: 210: 14.72		RBBP7_HUMAN (2-139): 7.36e-16: 83: 10.67
+	Hs
		903171 WDR5_HUMAN (42-354): 1.87e-63: 206: 16.51		RBBP4_HUMAN (2-139): 3.15e-16: 84.2: 10.00
+	Hs
		302275 WDR5_HUMAN (42-354): 1.87e-63: 206: 16.51		SC31A_HUMAN (5-185): 1.63e-15: 83.4: 9.68
+	Hs
		903551 NLE1_HUMAN (39-355): 1.01e-57: 196: 18.28		WDR5_HUMAN (222-464): 4.86e-19: 91.5: 8.00
+	Dm
		1358845 WDS_DROME (42-354): 8.62e-64: 208: 16.83		WDS_DROME (282-459): 3.36e-13: 74.2: 8.20
+	Hs
		903313 WDR5_HUMAN (42-354): 1.87e-63: 206: 16.51		WDR59_HUMAN (62-303): 1.21e-12: 74.1: 14.46
+	Ce
		954080 SEC13_CAEEL (55-335): 1.13e-43: 155: 18.56		LIN53_CAEEL (2-144): 1.02e-17: 88.4: 10.32