Interactor 1: AIM2 (Q91VJ1)
Interferon-inducible protein AIM2 (Interferon-inducible protein 210) (Ifi-210) (Interferon-inducible protein p210)
Gene: AIM2

Interactor 2: ASC (Q9EPB4)
Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein)
Gene: Pycard

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 37647255, 25327779
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PYRIN~PYRIN
Common GO terms GO:0002218 - activation of innate immune response
GO:0002221 - pattern recognition receptor signaling pathway
GO:0002230 - positive regulation of defense response to virus by host
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 10 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 354
Mm

1 193
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025