HitPredict

Interactor 1: Q9VCF4 (Q9VCF4)
AP complex subunit sigma
Gene: AP-1sigma

Interactor 2: Q9W388 (Q9W388)
AP-1 complex subunit gamma
Gene: AP-1gamma

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~Clat_adaptor_s
Common GO terms	GO:0006886 - intracellular protein transport GO:0030121 - AP-1 adaptor complex GO:0035615 - clathrin adaptor activity GO:0048749 - compound eye development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 157 Dm			1 963
+	Dm
		1182762 Q9VCF4_DROME (1-157): 3.54e-55: 172: 100.00		Q7KVR8_DROME (2-963): 0: 749: 98.86
+	Hs
		903681 AP1S1_HUMAN (1-157): 1.95e-51: 162: 75.95		AP2B1_HUMAN (58-936): 0: 601: 13.97
+	Hs
		880408 AP1S2_HUMAN (2-156): 6.01e-51: 161: 82.05		AP2B1_HUMAN (58-936): 0: 601: 13.97
+	Hs
		925978 AP1S3_HUMAN (1-153): 9.27e-50: 158: 71.24		AP2B1_HUMAN (58-936): 0: 601: 13.97
+	Hs
		903682 AP1S1_HUMAN (1-157): 1.95e-51: 162: 75.95		AP1B1_HUMAN (58-936): 0: 589: 14.30
+	Hs
		880409 AP1S2_HUMAN (2-156): 6.01e-51: 161: 82.05		AP1B1_HUMAN (58-936): 0: 589: 14.30
+	Hs
		1014066 AP1S3_HUMAN (1-153): 9.27e-50: 158: 71.24		AP1B1_HUMAN (58-936): 0: 589: 14.30
+	Ce
		725364 AP2M_CAEEL (1-155): 1.64e-45: 155: 18.68		Q22601_CAEEL (26-946): 0: 570: 20.17
+	Hs
		120009 AP3S1_HUMAN (1-153): 7.25e-50: 160: 34.59		AP3B1_HUMAN (56-955): 9.23e-176: 542: 13.42
+	Hs
		119942 AP3S2_HUMAN (1-153): 1.77e-48: 156: 35.22		AP3B1_HUMAN (56-955): 9.23e-176: 542: 13.42
+	Hs
		1032730 AP3S1_HUMAN (1-153): 7.25e-50: 160: 34.59		AP3B2_HUMAN (57-955): 2.45e-167: 519: 13.46
+	Ce
		725366 AP2M_CAEEL (1-155): 1.64e-45: 155: 18.68		Q9N4F3_CAEEL (58-935): 1.5e-166: 514: 15.41
+	Hs
		150247 AP3S1_HUMAN (1-153): 7.25e-50: 160: 34.59		AP3D1_HUMAN (35-662): 7.98e-154: 486: 21.28
+	Hs
		150196 AP3S2_HUMAN (1-153): 1.77e-48: 156: 35.22		AP3D1_HUMAN (35-662): 7.98e-154: 486: 21.28
+	Hs
		212614 AP1S1_HUMAN (1-157): 1.95e-51: 162: 75.95		AP1G1_HUMAN (266-955): 2.94e-45: 178: 12.66
+	Hs
		212611 AP1S2_HUMAN (2-156): 6.01e-51: 161: 82.05		AP1G1_HUMAN (266-955): 2.94e-45: 178: 12.66
+	Hs
		212659 AP1S3_HUMAN (1-153): 9.27e-50: 158: 71.24		AP1G1_HUMAN (266-955): 2.94e-45: 178: 12.66
+	Hs
		276362 AP1S1_HUMAN (1-157): 1.95e-51: 162: 75.95		AP1G2_HUMAN (266-953): 5.08e-33: 139: 14.54
+	Hs
		276360 AP1S2_HUMAN (2-156): 6.01e-51: 161: 82.05		AP1G2_HUMAN (266-953): 5.08e-33: 139: 14.54
+	Hs
		276385 AP1S3_HUMAN (1-153): 9.27e-50: 158: 71.24		AP1G2_HUMAN (266-953): 5.08e-33: 139: 14.54