Interactor 1: CSN6 (Q9VCY3)
COP9 signalosome complex subunit 6 (Dch6) (Signalosome subunit 6)
Gene: CSN6

Interactor 2: CSN5 (Q9XZ58)
COP9 signalosome complex subunit 5 (Dch5) (Signalosome subunit 5) (EC 3.4.-.-) (JAB1 homolog)
Gene: CSN5

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.800

The method score is based on:

Property Details
Experiments 25119050, 14605208
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CSN5_C~JAB, JAB~JAB, CSN5_C~MitMem_reg, JAB~MitMem_reg
Common GO terms GO:0000338 - protein deneddylation
GO:0005737 - cytoplasm
GO:0007281 - germ cell development
GO:0008180 - COP9 signalosome
GO:0036099 - female germ-line stem cell population maintenance
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 341
Dm

1 327
+ Hs
+ Mm
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Sc
+ Dm
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024