Interactor 1: RYR2 (Q92736)
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2
Interactor 2: JPH4 (Q96JJ6)
Junctophilin-4 (JP-4) (Junctophilin-like 1 protein)
Gene: JPH4
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.60 | 0.501 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31461656 |
| Identification Methods | fluorescent resonance energy transfer |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005790 - smooth endoplasmic reticulum GO:0005886 - plasma membrane GO:0010882 - regulation of cardiac muscle contraction by calcium ion signaling GO:0014701 - junctional sarcoplasmic reticulum membrane GO:0060402 - calcium ion transport into cytosol |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
