Interactor 1: SIRT1 (Q9VK34)
NAD-dependent histone deacetylase sirtuin-1 (EC 2.3.1.286) (Silent information regulator 2)
Gene: SIRT1

Interactor 2: Q9VPL9 (Q9VPL9)
FI24801p1 (KISMET-L long isoform) (Kismet, isoform A)
Gene: kis

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 27623778
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008340 - determination of adult lifespan
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 823
Dm

1 5322
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024