Interactor 1: TOR (Q9VK45)
Serine/threonine-protein kinase mTor (EC 2.7.11.1) (Target of rapamycin) (mechanistic Target of rapamycin)
Gene: mTor

Interactor 2: LST8 (Q9W328)
Protein LST8 homolog
Gene: LST8

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 22068330, 22493059
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~WD40
Common GO terms GO:0005737 - cytoplasm
GO:0031929 - TOR signaling
GO:0031932 - TORC2 complex
GO:0045793 - positive regulation of cell size
GO:0046628 - positive regulation of insulin receptor signaling pathway
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2470
Dm

1 313
+ Hs
+ Mm
+ Hs
+ Sp
+ At
+ At
+ Sp
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs

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Last updated: 15 Jul 2024