Interactor 1: POLH (Q9VNX1)
DNA polymerase eta (EC 2.7.7.7)
Gene: POLH

Interactor 2: REV1 (Q9W0P2)
DNA repair protein Rev1 (EC 2.7.7.-) (Reversionless protein 1)
Gene: REV1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 18242152
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IMS~IMS, IMS~IMS_C, IMS_C~IMS_C
Common GO terms GO:0003684 - damaged DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005634 - nucleus
GO:0005657 - replication fork
GO:0006302 - double-strand break repair
and 3 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 885
Dm

1 995
+ Dm
+ Sp
+ Sc
+ Hs
+ Hs
+ Hs
+ Mm
+ Sp
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs

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Last updated: 15 Jul 2024