HitPredict

Interactor 1: Q9W087 (Q9W087)
U6 snRNA-associated Sm-like protein LSm8
Gene: l(3)neo7

Interactor 2: Q9W2P5 (Q9W2P5)
RE43665p
Gene: DmelCG9344

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	22036573, 20353594
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005688 - U6 snRNP GO:0030532 - small nuclear ribonucleoprotein complex GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 95 Dm			1 79
+	Hs
		321386 LSM8_HUMAN (2-95): 1.25e-33: 113: 69.15		RUXF_HUMAN (1-73): 3.03e-33: 111: 47.95
+	Hs
		321388 LSM8_HUMAN (2-95): 1.25e-33: 113: 69.15		LSM6_HUMAN (3-79): 1.38e-33: 111: 85.71
+	Dm
		1369698 Q9W087_DROME (1-95): 1.1e-34: 115: 100.00		Q9VKW8_DROME (7-79): 5.22e-31: 107: 24.32
+	Hs
		321444 LSM8_HUMAN (2-95): 1.25e-33: 113: 69.15		LSM4_HUMAN (7-79): 1.85e-31: 108: 24.32
+	Dm
		1097032 Q9W087_DROME (1-95): 1.1e-34: 115: 100.00		RUXF_DROME (3-73): 7.31e-31: 105: 43.66
+	At
		1228011 LSM1B_ARATH (2-89): 6.13e-28: 99.5: 34.09		LSM6A_ARATH (5-79): 1.39e-31: 106: 74.67
+	Hs
		167678 LSM1_HUMAN (2-90): 3.41e-25: 93: 26.97		RUXF_HUMAN (1-73): 3.03e-33: 111: 47.95
+	Hs
		167681 LSM1_HUMAN (2-90): 3.41e-25: 93: 26.97		LSM6_HUMAN (3-79): 1.38e-33: 111: 85.71
+	Hs
		911801 RSMN_HUMAN (2-75): 3.88e-24: 93: 31.33		RUXF_HUMAN (1-73): 3.03e-33: 111: 47.95
+	Hs
		912220 RSMN_HUMAN (2-75): 3.88e-24: 93: 31.33		LSM6_HUMAN (3-79): 1.38e-33: 111: 85.71
+	Hs
		538890 RSMB_HUMAN (2-75): 1.3e-23: 91.4: 31.33		RUXF_HUMAN (1-73): 3.03e-33: 111: 47.95
+	Hs
		538893 RSMB_HUMAN (2-75): 1.3e-23: 91.4: 31.33		LSM6_HUMAN (3-79): 1.38e-33: 111: 85.71
+	Hs
		167728 LSM1_HUMAN (2-90): 3.41e-25: 93: 26.97		LSM4_HUMAN (7-79): 1.85e-31: 108: 24.32
+	Hs
		928049 RSMN_HUMAN (2-75): 3.88e-24: 93: 31.33		LSM4_HUMAN (7-79): 1.85e-31: 108: 24.32
+	Dm
		1374112 Q9W087_DROME (1-95): 1.1e-34: 115: 100.00		Q9VTW6_DROME (9-75): 2.23e-09: 50.7: 27.14
+	Hs
		321440 LSM8_HUMAN (2-95): 1.25e-33: 113: 69.15		LSM2_HUMAN (9-75): 1.16e-09: 51.5: 27.14
+	Hs
		167726 LSM1_HUMAN (2-90): 3.41e-25: 93: 26.97		LSM2_HUMAN (9-75): 1.16e-09: 51.5: 27.14
+	Hs
		928046 RSMN_HUMAN (2-75): 3.88e-24: 93: 31.33		LSM2_HUMAN (9-75): 1.16e-09: 51.5: 27.14
+	Dm
		1374114 Q9W2K2_DROME (2-90): 4.87e-25: 92.6: 28.09		Q9VTW6_DROME (9-75): 2.23e-09: 50.7: 27.14
+	Hs
		539197 RSMB_HUMAN (2-75): 1.3e-23: 91.4: 31.33		LSM2_HUMAN (9-75): 1.16e-09: 51.5: 27.14