Interactor 1: FAN1 (Q9Y2M0)
Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (hFAN1) (Myotubularin-related protein 15)
Gene: FAN1

Interactor 2: FAN1 (Q9Y2M0)
Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (hFAN1) (Myotubularin-related protein 15)
Gene: FAN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.90 0.809

The method score is based on:

Property Details
Experiments 27432908, 29518739, 20603015
Identification Methods affinity chromatography technology, x-ray crystallography, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains VRR_NUC~VRR_NUC
Common GO terms GO:0000287 - magnesium ion binding
GO:0000724 - double-strand break repair via homologous recombination
GO:0004528 - phosphodiesterase I activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 9 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024