Protein: TOM20
Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20)

Gene: TOM20, TOMM20
Organism: Homo sapiens
Interactions: 229
UniProt ID: Q15388

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005742 - mitochondrial outer membrane translocase complex
GO:0006626 - protein targeting to mitochondrion
GO:0015450 - protein-transporting ATPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

354338

TOM40
Mitochondrial import receptor subunit TOM40 homolog

5

6

Small-scale

0.709

High

1147691

TOM22
Mitochondrial import receptor subunit TOM22 homolog

5

1

Small-scale

0.703

High

1147623

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

4

1

Small-scale

0.676

High

1147674

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

3

1

Small-scale

0.646

High

640893

VDAC1
Non-selective voltage-gated ion channel VDAC1

2

5

Small-scale

0.619

High

1147595

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

2

High-throughput

0.618

High

683846

MOES
Moesin

3

0

High-throughput

0.613

High

901253

RAB7A
Ras-related protein Rab-7a

2

2

High-throughput

0.611

High

1125447

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

2

High-throughput

0.611

High

1147715

FBX7
F-box only protein 7

2

0

Small-scale

0.603

High

1147707

FEM1B
Protein fem-1 homolog B

2

1

High-throughput

0.601

High

318013

TOM70
Mitochondrial import receptor subunit TOM70

2

3

Small-scale

0.584

High

1147653

AKAP1
A-kinase anchor protein 1, mitochondrial

2

3

High-throughput

0.584

High

522101

BCL2
Apoptosis regulator Bcl-2

2

0

Small-scale

0.577

High

621477

HXK1
Hexokinase-1

2

1

High-throughput

0.571

High

852761

VDAC2
Non-selective voltage-gated ion channel VDAC2

2

5

High-throughput

0.571

High

914082

HXK2
Hexokinase-2

2

1

High-throughput

0.571

High

1147700

TOM7
Mitochondrial import receptor subunit TOM7 homolog

2

0

High-throughput

0.563

High

856704

BAG6
Large proline-rich protein BAG6

2

1

Small-scale

0.561

High

1147696

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.559

High

1147656

FAF2
FAS-associated factor 2

2

3

High-throughput

0.558

High

529847

TAU
Microtubule-associated protein tau

2

0

Small-scale

0.547

High

1147698

MIC19
MICOS complex subunit MIC19

2

0

High-throughput

0.547

High

928183

HAP1
Huntingtin-associated protein 1

1

2

High-throughput

0.541

High

359994

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.536

High

1147695

DJC11
DnaJ homolog subfamily C member 11

1

5

High-throughput

0.536

High

1147628

BPHL
Serine hydrolase BPHL

1

0

High-throughput

0.513

High

315616

RECQ4
ATP-dependent DNA helicase Q4

1

1

Small-scale

0.512

High

683070

UCP1
Mitochondrial brown fat uncoupling protein 1

1

3

Small-scale

0.501

High

1147670

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

Small-scale

0.501

High

277696

H2AY
Core histone macro-H2A.1

1

2

High-throughput

0.489

High

714140

PML
Protein PML

1

1

High-throughput

0.489

High

956302

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.489

High

981284

RAB1A
Ras-related protein Rab-1A

1

2

High-throughput

0.489

High

1016884

H33
Histone H3.3

1

1

High-throughput

0.489

High

1112847

CUL2
Cullin-2

1

1

High-throughput

0.489

High

1147599

H2A2C
Histone H2A type 2-C

1

1

High-throughput

0.489

High

1147631

H2A2B
Histone H2A type 2-B

1

1

High-throughput

0.489

High

1147643

NEDD1
Protein NEDD1

1

1

High-throughput

0.489

High

1147679

RAB1B
Ras-related protein Rab-1B

1

2

High-throughput

0.489

High

1147705

LIMA1
LIM domain and actin-binding protein 1

1

1

High-throughput

0.489

High

361634

OTC
Ornithine transcarbamylase, mitochondrial

1

0

Small-scale

0.480

High

791404

SYUA
Alpha-synuclein

1

0

Small-scale

0.480

High

135626

DNM1L
Dynamin-1-like protein

1

1

High-throughput

0.479

High

192254

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

209019

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.479

High

298718

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

1

High-throughput

0.479

High

343376

SNP29
Synaptosomal-associated protein 29

1

1

High-throughput

0.479

High

568422

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

665600

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

1

High-throughput

0.479

High

701828

ABCD3
ATP-binding cassette sub-family D member 3

1

2

High-throughput

0.479

High

784616

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

1

High-throughput

0.479

High

829400

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

4

High-throughput

0.479

High

869875

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

1

High-throughput

0.479

High

896243

PEX5
Peroxisomal targeting signal 1 receptor

1

1

High-throughput

0.479

High

1092544

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

5

High-throughput

0.479

High

1098705

NDK3
Nucleoside diphosphate kinase 3

1

1

High-throughput

0.479

High

1147596

MTFR1
Mitochondrial fission regulator 1

1

1

High-throughput

0.479

High

1147601

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

1147612

VP13D
Intermembrane lipid transfer protein VPS13D

1

1

High-throughput

0.479

High

1147614

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1147618

MTFR2
Mitochondrial fission regulator 2

1

1

High-throughput

0.479

High

1147633

MIRO2
Mitochondrial Rho GTPase 2

1

5

High-throughput

0.479

High

1147637

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.479

High

1147639

MIGA1
Mitoguardin 1

1

1

High-throughput

0.479

High

1147654

MARC2
Mitochondrial amidoxime reducing component 2

1

1

High-throughput

0.479

High

1147657

FXRD1
FAD-dependent oxidoreductase domain-containing protein 1

1

2

Small-scale

0.479

High

1147661

RMD2
Regulator of microtubule dynamics protein 2

1

1

High-throughput

0.479

High

1147663

VP13A
Intermembrane lipid transfer protein VPS13A

1

1

High-throughput

0.479

High

1147666

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

1147667

TTC1
Tetratricopeptide repeat protein 1

1

2

High-throughput

0.479

High

1147692

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.479

High

1147694

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

1147699

CISD1
CDGSH iron-sulfur domain-containing protein 1

1

1

High-throughput

0.479

High

1147711

TRAK1
Trafficking kinesin-binding protein 1

1

2

High-throughput

0.479

High

1147713

TDRKH
Tudor and KH domain-containing protein

1

3

High-throughput

0.479

High

1147717

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.479

High

1101966

PABP4
Polyadenylate-binding protein 4

1

1

High-throughput

0.470

High

71733

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.458

High

296242

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

319787

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

617517

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.458

High

732819

GLPK
Glycerol kinase

1

0

High-throughput

0.458

High

926087

DPOG1
DNA polymerase subunit gamma-1

1

0

Small-scale

0.458

High

959168

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

1034995

KPCE
Protein kinase C epsilon type

1

0

Small-scale

0.458

High

1147600

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

1

0

High-throughput

0.458

High

1147609

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

1

0

High-throughput

0.458

High

1147619

SARM1
NAD(+) hydrolase SARM1

1

0

Small-scale

0.458

High

1147620

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.458

High

1147626

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.458

High

1147665

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1147673

B2L13
Bcl-2-like protein 13

1

0

High-throughput

0.458

High

1147677

MFF
Mitochondrial fission factor

1

0

High-throughput

0.458

High

1147680

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.458

High

1147697

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

Small-scale

0.458

High

1147704

ARMX3
Armadillo repeat-containing X-linked protein 3

1

0

High-throughput

0.458

High

221585

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

1

High-throughput

0.445

High

245471

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

High-throughput

0.445

High

1147634

MIRO1
Mitochondrial Rho GTPase 1

1

5

High-throughput

0.445

High

1147645

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

2

High-throughput

0.445

High

1147712

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

5

High-throughput

0.445

High

135936

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

1

High-throughput

0.437

High

278865

PEX14
Peroxisomal membrane protein PEX14

1

2

High-throughput

0.437

High

281046

TACC1
Transforming acidic coiled-coil-containing protein 1

1

1

High-throughput

0.437

High

333017

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.437

High

334296

TACC2
Transforming acidic coiled-coil-containing protein 2

1

1

High-throughput

0.437

High

372095

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.437

High

406207

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.437

High

568810

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

1

High-throughput

0.437

High

588765

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

611131

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.437

High

668596

APC
Adenomatous polyposis coli protein

1

1

High-throughput

0.437

High

725499

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

1

High-throughput

0.437

High

755564

TTK
Dual specificity protein kinase TTK

1

1

High-throughput

0.437

High

828366

PEX19
Peroxisomal biogenesis factor 19

1

2

High-throughput

0.437

High

906057

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

3

High-throughput

0.437

High

915965

NUP98
Nuclear pore complex protein Nup98-Nup96

1

2

High-throughput

0.437

High

1015455

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.437

High

1096696

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.437

High

1099921

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

1107403

BIRC2
Baculoviral IAP repeat-containing protein 2

1

2

Small-scale

0.437

High

1115204

CUL4B
Cullin-4B

1

1

High-throughput

0.437

High

1137042

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

1

High-throughput

0.437

High

1147597

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

1

High-throughput

0.437

High

1147602

INF2
Inverted formin-2

1

1

High-throughput

0.437

High

1147603

MA7D1
MAP7 domain-containing protein 1

1

1

High-throughput

0.437

High

1147610

SE1L2
Protein sel-1 homolog 2

1

1

High-throughput

0.437

High

1147624

LARP4
La-related protein 4

1

1

High-throughput

0.437

High

1147636

NUP93
Nuclear pore complex protein Nup93

1

1

High-throughput

0.437

High

1147641

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

2

High-throughput

0.437

High

1147651

UBXN4
UBX domain-containing protein 4

1

2

High-throughput

0.437

High

1147659

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

1147664

MA7D2
MAP7 domain-containing protein 2

1

2

High-throughput

0.437

High

1147682

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

3

High-throughput

0.437

High

1147685

AGO3
Protein argonaute-3

1

1

High-throughput

0.437

High

1147688

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

2

High-throughput

0.437

High

1147706

CDC23
Cell division cycle protein 23 homolog

1

1

High-throughput

0.437

High

1147708

AGO2
Protein argonaute-2

1

1

High-throughput

0.437

High

1147710

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

2

High-throughput

0.437

High

257543

TI17B
Mitochondrial import inner membrane translocase subunit Tim17-B

1

0

High-throughput

0.426

High

1147638

TOM5
Mitochondrial import receptor subunit TOM5 homolog

1

0

High-throughput

0.426

High

1147687

PLRKT
Plasminogen receptor

1

0

High-throughput

0.426

High

1147616

CDC73
Parafibromin

1

1

High-throughput

0.417

High

299205

FLOT1
Flotillin-1

1

2

High-throughput

0.407

High

1124813

FLOT2
Flotillin-2

1

2

High-throughput

0.407

High

1147611

H37
Histone H3-7

1

1

High-throughput

0.407

High

1147662

FMNL2
Formin-like protein 2

1

2

High-throughput

0.407

High

163558

TPP1
Tripeptidyl-peptidase 1

2

0

High-throughput

0.318

High

387271

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.282

High

636735

PTN
Pleiotrophin

1

0

High-throughput

0.282

High

927307

ATX1
Ataxin-1

1

0

High-throughput

0.282

High

1147642

PPHLN
Periphilin-1

1

0

High-throughput

0.282

High

1147669

FEZ1
Fasciculation and elongation protein zeta-1

1

0

High-throughput

0.282

High

1147701

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

352766

F107A
Actin-associated protein FAM107A

1

0

High-throughput

0.279

Low

1147598

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.279

Low

1147649

NICA
Nicastrin

1

0

High-throughput

0.279

Low

1147684

ARP5
Actin-related protein 5

1

0

High-throughput

0.279

Low

1147703

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.279

Low

1147719

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.279

Low

1147720

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

0

High-throughput

0.279

Low

595439

H15
Histone H1.5

1

0

High-throughput

0.269

Low

1147622

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.269

Low

1147683

SYP2L
Synaptopodin 2-like protein

1

0

High-throughput

0.269

Low

1147693

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

0

Small-scale

0.251

Low

159352

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

0

High-throughput

0.249

Low

213937

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.249

Low

223067

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.249

Low

291347

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

293729

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

517532

GLI3
Transcriptional activator GLI3

1

0

High-throughput

0.249

Low

563805

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.249

Low

627661

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.249

Low

629885

BTF3
Transcription factor BTF3

1

0

High-throughput

0.249

Low

695531

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768260

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

830787

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

857111

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.249

Low

945234

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.249

Low

959797

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.249

Low

961300

RL27
Large ribosomal subunit protein eL27

1

0

High-throughput

0.249

Low

970549

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1040300

DYST
Dystonin

1

0

High-throughput

0.249

Low

1063123

GOGA3
Golgin subfamily A member 3

1

0

High-throughput

0.249

Low

1085221

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.249

Low

1091856

ABR
Active breakpoint cluster region-related protein

1

0

High-throughput

0.249

Low

1147604

TGO1
Transport and Golgi organization protein 1 homolog

1

0

High-throughput

0.249

Low

1147605

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.249

Low

1147606

FA83B
Protein FAM83B

1

0

High-throughput

0.249

Low

1147607

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.249

Low

1147613

OTUD1
OTU domain-containing protein 1

1

0

Small-scale

0.249

Low

1147615

CRBG3
Very large A-kinase anchor protein

1

0

High-throughput

0.249

Low

1147617

SCYL2
SCY1-like protein 2

1

0

High-throughput

0.249

Low

1147621

SAS6
Spindle assembly abnormal protein 6 homolog

1

0

High-throughput

0.249

Low

1147625

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.249

Low

1147627

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1147629

PRSR1
Proline and serine-rich protein 1

1

0

High-throughput

0.249

Low

1147630

DTX1
E3 ubiquitin-protein ligase DTX1

1

0

Small-scale

0.249

Low

1147632

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

1147635

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

1147640

EHBP1
EH domain-binding protein 1

1

0

High-throughput

0.249

Low

1147644

MAFA
Transcription factor MafA

1

0

High-throughput

0.249

Low

1147646

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

High-throughput

0.249

Low

1147647

NU133
Nuclear pore complex protein Nup133

1

0

High-throughput

0.249

Low

1147648

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.249

Low

1147650

TM131
Transmembrane protein 131

1

0

High-throughput

0.249

Low

1147652

NU205
Nuclear pore complex protein Nup205

1

0

High-throughput

0.249

Low

1147655

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.249

Low

1147658

OPTN
Optineurin

1

0

High-throughput

0.249

Low

1147660

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1147668

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.249

Low

1147671

GPTC1
G patch domain-containing protein 1

1

0

High-throughput

0.249

Low

1147672

TRPM6
Transient receptor potential cation channel subfamily M member 6

1

0

High-throughput

0.249

Low

1147675

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

1147676

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.249

Low

1147678

LSG1
Large subunit GTPase 1 homolog

1

0

High-throughput

0.249

Low

1147681

CA198
Uncharacterized protein C1orf198

1

0

High-throughput

0.249

Low

1147686

WDR41
WD repeat-containing protein 41

1

0

High-throughput

0.249

Low

1147689

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.249

Low

1147690

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.249

Low

1147702

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1147709

SUFU
Suppressor of fused homolog

1

0

High-throughput

0.249

Low

1147714

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.249

Low

1147716

TRAF6
TNF receptor-associated factor 6

1

0

Small-scale

0.249

Low

1147718

YTHD2
YTH domain-containing family protein 2

1

0

High-throughput

0.249

Low

429934

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low

1147608

RN187
E3 ubiquitin-protein ligase RNF187

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025