HitPredict

Interactor 1: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: TNR11 (Q9Y6Q6)
Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265)
Gene: TNFRSF11A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.758

The method score is based on:

Property Details
Experiments 35463988, 26038599, 27507811, 11809792, 9685412, 10075662, 9852070, 10025951, 9774460, 11406619
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001503 - ossification
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030316 - osteoclast differentiation
GO:0033209 - tumor necrosis factor-mediated signaling pathway
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 522
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024