HitPredict

Interactor 1: AP4S1 (Q9Y587)
AP-4 complex subunit sigma-1 (AP-4 adaptor complex subunit sigma-1) (Adaptor-related protein complex 4 subunit sigma-1) (Sigma-1 subunit of AP-4) (Sigma-4-adaptin) (Sigma4-adaptin)
Gene: AP4S1

Interactor 2: AP4B1 (Q9Y6B7)
AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin)
Gene: AP4B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 26496610, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adaptin_N~Clat_adaptor_s
Common GO terms GO:0005802 - trans-Golgi network
GO:0006605 - protein targeting
GO:0008104 - protein localization
GO:0016192 - vesicle-mediated transport
GO:0030124 - AP-4 adaptor complex
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 144
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024