Protein: MLF1
Myeloid leukemia factor 1 (Myelodysplasia-myeloid leukemia factor 1)

Gene: MLF1
Organism: Homo sapiens
Interactions: 199
UniProt ID: P58340

Gene Ontology (top 5):
GO:0002318 - myeloid progenitor cell differentiation
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005929 - cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

274521

DNJB6
DnaJ homolog subfamily B member 6

5

13

High-throughput

0.714

High

946171

DNJB8
DnaJ homolog subfamily B member 8

4

13

High-throughput

0.691

High

224099

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

3

1

High-throughput

0.667

High

651635

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

3

2

High-throughput

0.667

High

946096

TROP
Trophinin

3

2

High-throughput

0.667

High

946103

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

3

3

High-throughput

0.667

High

946189

CK5P2
CDK5 regulatory subunit-associated protein 2

3

2

High-throughput

0.667

High

946196

AASD1
Alanyl-tRNA editing protein Aarsd1

3

1

High-throughput

0.667

High

848853

MAGAB
Melanoma-associated antigen 11

3

2

High-throughput

0.666

High

946152

FA83H
Protein FAM83H

4

0

High-throughput

0.661

High

946175

ALMS1
Centrosome-associated protein ALMS1

4

0

High-throughput

0.661

High

946221

SYNRG
Synergin gamma

4

0

High-throughput

0.661

High

124289

HAX1
HCLS1-associated protein X-1

3

1

High-throughput

0.656

High

946139

MYOME
Myomegalin

3

1

High-throughput

0.656

High

329912

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

3

0

High-throughput

0.638

High

904267

BRCA2
Breast cancer type 2 susceptibility protein

3

0

High-throughput

0.638

High

913449

KIF11
Kinesin-like protein KIF11

3

0

High-throughput

0.638

High

946120

ERC6L
DNA excision repair protein ERCC-6-like

3

0

High-throughput

0.638

High

946124

GRDN
Girdin

3

0

High-throughput

0.638

High

946170

KNL1
Outer kinetochore KNL1 complex subunit KNL1

3

0

High-throughput

0.638

High

946195

HAUS8
HAUS augmin-like complex subunit 8

3

0

High-throughput

0.638

High

946200

DSN1
Kinetochore-associated protein DSN1 homolog

3

0

High-throughput

0.638

High

946218

AKA11
A-kinase anchor protein 11

3

0

High-throughput

0.638

High

946209

HTR5B
HEAT repeat-containing protein 5B

3

0

Small-scale

0.628

High

186725

P73
Tumor protein p73

2

2

High-throughput

0.611

High

679320

DNJB2
DnaJ homolog subfamily B member 2

2

12

High-throughput

0.611

High

946222

CHIP
E3 ubiquitin-protein ligase CHIP

2

2

High-throughput

0.611

High

163914

NDC80
Kinetochore protein NDC80 homolog

2

0

High-throughput

0.602

High

946098

CDC16
Cell division cycle protein 16 homolog

2

0

High-throughput

0.602

High

946199

CE295
Centrosomal protein of 295 kDa

2

0

High-throughput

0.602

High

861089

MAP1B
Microtubule-associated protein 1B

2

0

High-throughput

0.585

High

946198

DUS16
Dual specificity protein phosphatase 16

2

0

High-throughput

0.585

High

946225

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

0

High-throughput

0.576

High

596968

TSHR
Thyrotropin receptor

2

1

High-throughput

0.574

High

346934

BAG2
BAG family molecular chaperone regulator 2

2

2

High-throughput

0.558

High

946213

DNJB4
DnaJ homolog subfamily B member 4

2

7

High-throughput

0.549

High

336647

BAG4
BAG family molecular chaperone regulator 4

1

6

High-throughput

0.536

High

536853

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.536

High

650536

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

2

High-throughput

0.536

High

679121

DNJB1
DnaJ homolog subfamily B member 1

1

7

High-throughput

0.536

High

848603

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.536

High

927207

ATX1
Ataxin-1

1

2

High-throughput

0.536

High

946097

TRAF2
TNF receptor-associated factor 2

1

1

High-throughput

0.536

High

946161

AN13A
Ankyrin repeat domain-containing protein 13A

1

3

High-throughput

0.536

High

946188

KI20B
Kinesin-like protein KIF20B

1

1

High-throughput

0.536

High

946192

NPAS1
Neuronal PAS domain-containing protein 1

1

4

High-throughput

0.536

High

946201

WNK1
Serine/threonine-protein kinase WNK1

1

5

High-throughput

0.536

High

946215

NRBP
Nuclear receptor-binding protein

1

3

High-throughput

0.536

High

946217

HSPB8
Heat shock protein beta-8

1

3

High-throughput

0.536

High

946219

BAG5
BAG family molecular chaperone regulator 5

1

6

High-throughput

0.536

High

946092

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.513

High

48138

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.513

High

144241

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.513

High

889955

PSN1
Presenilin-1

1

0

High-throughput

0.513

High

946111

PLEC
Plectin

1

0

High-throughput

0.513

High

946132

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

0

High-throughput

0.513

High

946133

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

946136

OTUD3
OTU domain-containing protein 3

1

0

High-throughput

0.513

High

946149

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.513

High

946177

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

946186

ANM6
Protein arginine N-methyltransferase 6

1

0

High-throughput

0.513

High

946173

COP1
E3 ubiquitin-protein ligase COP1

1

1

Small-scale

0.512

High

946153

CENPU
Centromere protein U

1

0

Small-scale

0.504

High

850770

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

1

High-throughput

0.489

High

946109

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.489

High

946191

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

1

High-throughput

0.489

High

163626

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

7

High-throughput

0.479

High

207954

TET3
Methylcytosine dioxygenase TET3

1

1

High-throughput

0.479

High

210905

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

3

High-throughput

0.479

High

271317

ZBED4
Zinc finger BED domain-containing protein 4

1

3

High-throughput

0.479

High

326141

REC8
Meiotic recombination protein REC8 homolog

1

1

High-throughput

0.479

High

347608

BAG3
BAG family molecular chaperone regulator 3

1

6

High-throughput

0.479

High

364124

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

1

High-throughput

0.479

High

400564

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

410743

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.479

High

425408

ISG15
Ubiquitin-like protein ISG15

1

2

Small-scale

0.479

High

618448

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

1

5

High-throughput

0.479

High

622787

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

1

High-throughput

0.479

High

723656

CALCR
Calcitonin receptor

1

1

High-throughput

0.479

High

755863

MCM5
DNA replication licensing factor MCM5

1

3

High-throughput

0.479

High

756140

MCM7
DNA replication licensing factor MCM7

1

3

High-throughput

0.479

High

846734

GRK6
G protein-coupled receptor kinase 6

1

5

High-throughput

0.479

High

946090

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.479

High

946091

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

2

High-throughput

0.479

High

946093

ERF1
Eukaryotic peptide chain release factor subunit 1

1

1

High-throughput

0.479

High

946094

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

7

High-throughput

0.479

High

946099

NR1H3
Oxysterols receptor LXR-alpha

1

1

High-throughput

0.479

High

946100

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.479

High

946101

SKP2
S-phase kinase-associated protein 2

1

1

High-throughput

0.479

High

946104

SIM2
Single-minded homolog 2

1

4

High-throughput

0.479

High

946110

SETB1
Histone-lysine N-methyltransferase SETDB1

1

2

High-throughput

0.479

High

946114

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

2

High-throughput

0.479

High

946115

MLF2
Myeloid leukemia factor 2

1

1

High-throughput

0.479

High

946116

TBCE
Tubulin-specific chaperone E

1

2

High-throughput

0.479

High

946117

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.479

High

946122

KLH38
Kelch-like protein 38

1

1

High-throughput

0.479

High

946137

Q5T7U4
General transcription factor IIIC subunit 5

1

1

High-throughput

0.479

High

946155

GET4
Golgi to ER traffic protein 4 homolog

1

1

High-throughput

0.479

High

946164

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

946172

Q8NHX6
DNA replication licensing factor MCM3

1

4

High-throughput

0.479

High

946178

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

1

High-throughput

0.479

High

946181

TRI43
Tripartite motif-containing protein 43

1

1

High-throughput

0.479

High

946193

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

946197

Q9BWF4
DNA helicase

1

6

High-throughput

0.479

High

946202

TBB1
Tubulin beta-1 chain

1

2

High-throughput

0.479

High

946206

HYPK
Huntingtin-interacting protein K

1

1

Small-scale

0.479

High

946207

TLR7
Toll-like receptor 7

1

1

High-throughput

0.479

High

946210

E2AK4
eIF-2-alpha kinase GCN2

1

1

High-throughput

0.479

High

946211

HDAC6
Protein deacetylase HDAC6

1

1

High-throughput

0.479

High

946214

Z3H7B
Zinc finger CCCH domain-containing protein 7B

1

3

High-throughput

0.479

High

946220

UBP18
Ubl carboxyl-terminal hydrolase 18

1

1

High-throughput

0.479

High

946223

CSN3
COP9 signalosome complex subunit 3

1

3

Small-scale

0.479

High

946224

TRI17
E3 ubiquitin-protein ligase TRIM17

1

1

High-throughput

0.479

High

893781

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.460

High

73699

B2RC52
ATP-sensitive inward rectifier potassium channel 11

1

0

High-throughput

0.458

High

341543

EYA4
Protein phosphatase EYA4

1

0

High-throughput

0.458

High

403151

APOB
Apolipoprotein B-100

1

0

High-throughput

0.458

High

719605

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

0

High-throughput

0.458

High

887405

CEBPD
CCAAT/enhancer-binding protein delta

1

0

Small-scale

0.458

High

946095

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.458

High

946102

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

0

High-throughput

0.458

High

946113

TRBP2
RISC-loading complex subunit TARBP2

1

0

High-throughput

0.458

High

946121

Q2TAK1
F-box DNA helicase 1

1

0

High-throughput

0.458

High

946123

EDRF1
Erythroid differentiation-related factor 1

1

0

High-throughput

0.458

High

946131

TFDP3
Transcription factor Dp family member 3

1

0

High-throughput

0.458

High

946157

GTD2A
General transcription factor II-I repeat domain-containing protein 2A

1

0

High-throughput

0.458

High

946158

Q86WA0
ATP-dependent RNA helicase TDRD9

1

0

High-throughput

0.458

High

946159

I2BP1
Interferon regulatory factor 2-binding protein 1

1

0

High-throughput

0.458

High

946160

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.458

High

946179

Q93000
CHL1 protein

1

0

High-throughput

0.458

High

946190

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

0

High-throughput

0.458

High

946203

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

298896

DNJB5
DnaJ homolog subfamily B member 5

1

7

High-throughput

0.445

High

946150

GASP3
G protein-coupled receptor associated sorting protein 3

1

1

High-throughput

0.445

High

75879

B4DE84
cDNA FLJ55955, highly similar to HECT domain and RCC1-like domain-containing protein 2

1

1

High-throughput

0.437

High

160457

IRS4
Insulin receptor substrate 4

1

1

High-throughput

0.437

High

273510

DJC13
DnaJ homolog subfamily C member 13

1

12

High-throughput

0.437

High

292108

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

3

High-throughput

0.437

High

721448

GNA15
Guanine nucleotide-binding protein subunit alpha-15

1

6

High-throughput

0.437

High

846006

CACP
Carnitine O-acetyltransferase

1

1

High-throughput

0.437

High

946105

RCN2
Reticulocalbin-2

1

4

High-throughput

0.437

High

946108

Q149M6
Exophilin 5

1

1

High-throughput

0.437

High

946112

RCN1
Reticulocalbin-1

1

4

High-throughput

0.437

High

946125

Q4G1B2
Regulator of G-protein signaling 9

1

1

High-throughput

0.437

High

946126

EIPR1
EARP and GARP complex-interacting protein 1

1

1

High-throughput

0.437

High

946128

Q59FM5
Guanine nucleotide-binding protein subunit alpha

1

5

High-throughput

0.437

High

946129

Q59G26
Guanine nucleotide-binding protein, beta-3 subunit variant

1

7

High-throughput

0.437

High

946130

Q59H13
exodeoxyribonuclease III

1

1

High-throughput

0.437

High

946138

Q5ULA9
Monoamine oxidase A

1

1

High-throughput

0.437

High

946145

Q6FHF7
Geranylgeranyl transferase type-2 subunit alpha

1

1

High-throughput

0.437

High

946146

Q6FHM2
Epididymis secretory sperm binding protein

1

7

High-throughput

0.437

High

946147

Q6IAW5
Calumenin

1

4

High-throughput

0.437

High

946154

Q76GR4
Ligase I, DNA, ATP-dependent

1

1

High-throughput

0.437

High

946174

HUS1B
Checkpoint protein HUS1B

1

1

High-throughput

0.437

High

946180

Q96BE0
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.437

High

946185

Q96II5
non-specific serine/threonine protein kinase

1

2

High-throughput

0.437

High

946205

DBLOH
Diablo IAP-binding mitochondrial protein

1

1

High-throughput

0.437

High

946216

FKBPL
FK506-binding protein-like

1

1

High-throughput

0.437

High

946134

RBG1L
Rab GTPase-activating protein 1-like

1

0

High-throughput

0.426

High

946194

TCF25
Ribosome quality control complex subunit TCF25

1

0

High-throughput

0.426

High

946107

SL9A5
Sodium/hydrogen exchanger 5

1

1

High-throughput

0.407

High

946148

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

3

High-throughput

0.407

High

946168

EXPH5
Exophilin-5

1

1

High-throughput

0.407

High

946212

SL9A2
Sodium/hydrogen exchanger 2

1

1

High-throughput

0.407

High

725369

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

3

0

High-throughput

0.347

High

946156

HAUS6
HAUS augmin-like complex subunit 6

3

0

High-throughput

0.347

High

946182

ATG2B
Autophagy-related protein 2 homolog B

3

0

High-throughput

0.347

High

946142

WAC2A
WASH complex subunit 2A

3

0

High-throughput

0.339

High

946143

CRBG3
Very large A-kinase anchor protein

3

0

High-throughput

0.339

High

653717

PROZ
Vitamin K-dependent protein Z

2

0

High-throughput

0.328

High

946151

THSD4
Thrombospondin type-1 domain-containing protein 4

2

0

High-throughput

0.328

High

85247

RBG10
Rab GTPase-activating protein 1-like, isoform 10

2

0

High-throughput

0.318

High

946166

SPC24
Kinetochore protein Spc24

2

0

High-throughput

0.318

High

630236

TNR1B
Tumor necrosis factor receptor superfamily member 1B

2

0

High-throughput

0.313

High

946208

GPC5B
G-protein coupled receptor family C group 5 member B

2

0

High-throughput

0.313

High

946119

GRIK5
Glutamate receptor ionotropic, kainate 5

1

0

High-throughput

0.282

High

217414

E41L2
Band 4.1-like protein 2

1

0

High-throughput

0.279

Low

370407

KNG1
Kininogen-1

1

0

High-throughput

0.279

Low

946106

BLTP2
Bridge-like lipid transfer protein family member 2

1

0

High-throughput

0.279

Low

946135

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

946144

SCAR3
Scavenger receptor class A member 3

1

0

High-throughput

0.279

Low

946162

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

946165

PRLD2
PRELI domain-containing protein 2

1

0

High-throughput

0.279

Low

946167

RELL2
RELT-like protein 2

1

0

High-throughput

0.279

Low

946169

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.279

Low

946183

BORC8
BLOC-1-related complex subunit 8

1

0

High-throughput

0.279

Low

946184

MRAP2
Melanocortin-2 receptor accessory protein 2

1

0

High-throughput

0.279

Low

946187

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

946118

UT2
Urea transporter 2

1

0

High-throughput

0.269

Low

69426

A8K251
Zinc finger and BTB domain-containing protein 20

1

0

High-throughput

0.249

Low

907664

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.249

Low

946127

Q573B4
Tyrosine-protein kinase

1

0

High-throughput

0.249

Low

946140

FYB2
FYN-binding protein 2

1

0

High-throughput

0.249

Low

946163

Q8N5Q5
Uncharacterized protein

1

0

High-throughput

0.249

Low

946176

Q8TDZ3
MYHbeta

1

0

High-throughput

0.249

Low

946204

Q9NQR3
BRCAI

1

0

High-throughput

0.249

Low

873722

GSH0
Glutamate--cysteine ligase regulatory subunit

1

0

High-throughput

0.232

Low

946141

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025