Interactor 1: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 21953935, 25702872, 28292943, 34761751, 18922472, 24752541
Identification Methods pull down, affinity chromatography technology, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C12~Peptidase_C12, Peptidase_C12~UCH_C
Common GO terms GO:0000723 - telomere maintenance
GO:0003723 - RNA binding
GO:0004843 - cysteine-type deubiquitinase activity
GO:0004866 - endopeptidase inhibitor activity
GO:0005634 - nucleus
and 27 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 329
Hs

1 329
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024