Protein: SYS
Serine--tRNA ligase (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)

Gene: SYS, serS
Organism: Escherichia coli K-12
Interactions: 18
UniProt ID: P0A8L1

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004828 - serine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006434 - seryl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

495494

SYS
Serine--tRNA ligase

3

15

Small-scale

0.850

High

495495

SYK2
Lysine--tRNA ligase, heat inducible

2

13

High-throughput

0.588

High

495498

SSPA
Stringent starvation protein A

2

3

High-throughput

0.588

High

492309

RECF
DNA replication and repair protein RecF

2

0

High-throughput

0.576

High

495505

YFJD
UPF0053 inner membrane protein YfjD

2

1

High-throughput

0.549

High

489506

CH60
Chaperonin GroEL

1

5

High-throughput

0.536

High

495496

CSPE
Cold shock-like protein CspE

1

4

High-throughput

0.484

High

495497

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.464

High

495500

YJFN
Uncharacterized protein YjfN

2

0

High-throughput

0.313

High

495503

YEIR
Zinc chaperone YeiR

2

0

High-throughput

0.313

High

495504

BCSB
Cyclic di-GMP-binding protein

2

0

High-throughput

0.313

High

423987

3MG1
DNA-3-methyladenine glycosylase 1

2

0

High-throughput

0.307

High

495501

GATZ
D-tagatose-1,6-bisphosphate aldolase subunit GatZ

1

0

High-throughput

0.279

Low

495502

YIDF
Uncharacterized protein YidF

1

0

High-throughput

0.279

Low

495506

FADH
2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

1

0

High-throughput

0.279

Low

495507

YDIZ
Uncharacterized protein YdiZ

1

0

High-throughput

0.279

Low

495499

DMA
DNA adenine methylase

1

0

High-throughput

0.253

Low


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Last updated: 11Aug2025