HitPredict

Interactor 1: TIFA (Q96CG3)
TRAF-interacting protein with FHA domain-containing protein A (Putative MAPK-activating protein PM14) (Putative NF-kappa-B-activating protein 20) (TRAF2-binding protein)
Gene: TIFA

Interactor 2: SDCB2 (Q9H190)
Syntenin-2 (Similar to TACIP18) (SITAC) (Syndecan-binding protein 2)
Gene: SDCBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.688

Property	Details
Experiments	25416956, 16189514, 27107012
Identification Methods	two hybrid, validated two hybrid, barcode fusion genetics two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 184 Hs			1 292
+	Hs
		140394 TIFA_HUMAN (1-184): 2.16e-97: 281: 100.00		SDCB1_HUMAN (3-291): 3.93e-81: 248: 58.45
+	Hs
		1325745 TIFA_HUMAN (1-184): 2.16e-97: 281: 100.00		LNX2_HUMAN (16-264): 3.56e-27: 112: 15.87
+	Hs
		1348410 TIFA_HUMAN (1-184): 2.16e-97: 281: 100.00		LNX1_HUMAN (190-278): 1.01e-10: 64.1: 15.31