HitPredict

Interactor 1: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Interactor 2: DLRB1 (Q9NP97)
Dynein light chain roadblock-type 1 (Bithoraxoid-like protein) (BLP) (Dynein light chain 2A, cytoplasmic) (Dynein-associated protein Km23) (Roadblock domain-containing protein 1)
Gene: DYNLRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27173435, 28718761
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005868 - cytoplasmic dynein complex GO:0005929 - cilium GO:0097542 - ciliary tip
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 96
+	Hs
		1353474 DC2I2_HUMAN (1-536): 9.46e-110: 339: 100.00		DLRB2_HUMAN (1-96): 3.83e-43: 137: 77.08
+	Ce
		233703 O45087_CAEEL (88-534): 6.52e-87: 282: 18.63		Q22752_CAEEL (1-93): 6.49e-34: 113: 49.46
+	Dm
		1173000 DYIN_DROME (67-535): 1.07e-77: 259: 20.87		Q7KMS3_DROME (3-96): 5.8e-41: 131: 74.47
+	Hs
		1104265 DC1I2_HUMAN (77-536): 4.45e-72: 243: 19.96		DLRB1_HUMAN (1-96): 3.92e-43: 137: 100.00
+	Hs
		156669 DC1I1_HUMAN (11-536): 6.63e-70: 237: 18.44		DLRB1_HUMAN (1-96): 3.92e-43: 137: 100.00
+	Hs
		845335 LIS1_HUMAN (262-536): 9.67e-64: 215: 11.63		DLRB2_HUMAN (1-96): 3.83e-43: 137: 77.08
+	Hs
		1353472 DC2I1_HUMAN (63-496): 4.08e-27: 118: 19.05		DLRB2_HUMAN (1-96): 3.83e-43: 137: 77.08
+	Hs
		1358517 DC2I1_HUMAN (63-496): 4.08e-27: 118: 19.05		DLRB1_HUMAN (1-96): 3.92e-43: 137: 100.00