HitPredict

Interactor 1: DGKZ (O08560)
Diacylglycerol kinase zeta (DAG kinase zeta) (EC 2.7.1.107) (EC 2.7.1.93) (104 kDa diacylglycerol kinase) (DGK-IV) (Diglyceride kinase zeta) (DGK-zeta)
Gene: DGKZ

Interactor 2: DLG2 (Q63622)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.708

Property	Details
Experiments	19229292
Identification Methods	anti bait coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0098978 - glutamatergic synapse GO:0099562 - maintenance of postsynaptic density structure
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 929 Rn			1 852
+	Rn
		94385 DGKI_RAT (38-928): 0: 827: 61.38		DLG2_RAT (1-852): 0: 751: 100.00
+	Rn
		139212 DGKZ_RAT (1-928): 0: 958: 100.00		DLG1_RAT (9-852): 4.45e-164: 502: 51.95
+	Rn
		94383 DGKI_RAT (38-928): 0: 827: 61.38		DLG1_RAT (9-852): 4.45e-164: 502: 51.95
+	Rn
		139209 DGKZ_RAT (1-928): 0: 958: 100.00		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Rn
		139213 DGKZ_RAT (1-928): 0: 958: 100.00		DLG3_RAT (10-391): 7.38e-29: 126: 17.87
+	Rn
		94382 DGKI_RAT (38-928): 0: 827: 61.38		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Rn
		94384 DGKI_RAT (38-928): 0: 827: 61.38		DLG3_RAT (10-391): 7.38e-29: 126: 17.87
+	Rn
		1144016 TANC1_RAT (494-929): 5.03e-67: 247: 13.66		DLG1_RAT (9-852): 4.45e-164: 502: 51.95
+	Hs
		1021559 TANC1_HUMAN (555-880): 2.44e-27: 122: 13.33		DLG1_HUMAN (7-852): 4.33e-169: 515: 53.34
+	Mm
		1012698 TANC1_MOUSE (494-929): 3.38e-67: 248: 13.44		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Rn
		677797 TANC1_RAT (494-929): 5.03e-67: 247: 13.66		DLG4_RAT (4-419): 7.48e-31: 131: 17.37
+	Mm
		1143421 ANK2_MOUSE (690-929): 9.92e-47: 184: 14.13		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Mm
		103602 ANK3_MOUSE (701-929): 1.97e-36: 151: 16.17		DLG4_MOUSE (4-419): 3.42e-31: 132: 17.37
+	Hs
		942379 TANC1_HUMAN (555-880): 2.44e-27: 122: 13.33		DLG4_HUMAN (4-419): 6.5e-31: 132: 17.37