HitPredict

Interactor 1: DDRGK (Q96HY6)
DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1)
Gene: DDRGK1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35384245, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 314 Hs			1 1620
+	Hs
		464031 DDRGK_HUMAN (1-314): 5.31e-64: 206: 100.00		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		477253 DDRGK_HUMAN (1-314): 5.31e-64: 206: 100.00		ROS1_HUMAN (1039-1461): 3.97e-112: 397: 37.75
+	Hs
		439821 DDRGK_HUMAN (1-314): 5.31e-64: 206: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465616 DDRGK_HUMAN (1-314): 5.31e-64: 206: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		1157030 DDRGK_HUMAN (1-314): 5.31e-64: 206: 100.00		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		541639 DDRGK_HUMAN (1-314): 5.31e-64: 206: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07