Interactor 1: CLOCK (O08785)
Circadian locomoter output cycles protein kaput (mCLOCK) (EC 2.3.1.48)
Gene: CLOCK

Interactor 2: PER2 (O54943)
Period circadian protein homolog 2 (mPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 18662546, 14701732, 16717091, 22274616, 21680841, 18430226, 20832105, 23555304
Identification Methods affinity chromatography technology, gal4 vp16 complementation, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAS~PAS_3, PAS_11~PAS_3
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 855
Mm

1 1257
+ Hs
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+ Dr
+ Hs
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+ Mm

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Last updated: 15 Jul 2024