Interactor 1: CLIC6 (Q96NY7)
Chloride intracellular channel protein 6 (Glutaredoxin-like oxidoreductase CLIC6) (EC 1.8.-.-) (Parchorin)
Gene: CLIC6

Interactor 2: CLIC4 (Q9Y696)
Chloride intracellular channel protein 4 (Glutaredoxin-like oxidoreductase CLIC4) (EC 1.8.-.-) (Intracellular chloride ion channel protein p64H1)
Gene: CLIC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.905

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35914814
Identification Methods affinity chromatography technology, two hybrid, two hybrid fragment pooling approach, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CLIC-like_N~CLIC-like_N
Common GO terms GO:0005254 - chloride channel activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0016491 - oxidoreductase activity
GO:0034707 - chloride channel complex
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 704
Hs

1 253
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+ Ce
+ At
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Last updated: 11Aug2025