Interactor 1: CLIC2 (O15247)
Chloride intracellular channel protein 2 (Glutaredoxin-like oxidoreductase CLIC2) (EC 1.8.-.-) (Glutaredoxin-like peroxidase CLIC2) (EC 1.11.1.-) (XAP121)
Gene: CLIC2

Interactor 2: CLIC5 (Q9NZA1)
Chloride intracellular channel protein 5 (Glutaredoxin-like oxidoreductase CLIC5) (EC 1.8.-.-)
Gene: CLIC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CLIC-like_N~CLIC-like_N, CLIC-like_N~GST_C_2, GST_C_2~GST_C_2
Common GO terms GO:0005254 - chloride channel activity
GO:0006821 - chloride transport
GO:0034707 - chloride channel complex
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 247
Hs

1 410
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Ce
+ At
+ At
+ Hs
+ Hs
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025