HitPredict

Interactor 1: BIN1 (O08839)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1)
Gene: BIN1

Interactor 2: Q66HM2 (Q66HM2)
AP-2 complex subunit alpha
Gene: Ap2a2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	17762867
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Rn			1 939
+	Hs
		131185 BIN1_HUMAN (1-587): 1.85e-121: 373: 93.76		AP2A2_HUMAN (1-939): 0: 866: 95.85
+	Rn
		88754 BIN1_RAT (1-588): 4.99e-132: 400: 100.00		D3ZUY8_RAT (1-939): 0: 836: 81.25
+	Hs
		131189 BIN1_HUMAN (1-587): 1.85e-121: 373: 93.76		AP2A1_HUMAN (1-939): 0: 833: 78.67
+	Rn
		139988 BIN1_RAT (1-588): 4.99e-132: 400: 100.00		AP2B1_RAT (36-934): 0: 629: 16.82
+	Rn
		1144064 SYNJ1_RAT (156-585): 1.28e-15: 83: 12.04		Q66HM2_RAT (1-939): 0: 892: 100.00
+	Mm
		567528 AMPH_MOUSE (43-588): 1.62e-14: 78.8: 17.03		AP2A2_MOUSE (1-939): 0: 889: 99.57
+	Rn
		139980 AMPH_RAT (91-588): 1.14e-11: 69.5: 16.51		Q66HM2_RAT (1-939): 0: 892: 100.00
+	Hs
		302118 AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97		AP2A2_HUMAN (1-939): 0: 866: 95.85
+	Hs
		321511 AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97		AP2A1_HUMAN (1-939): 0: 833: 78.67
+	Hs
		203194 SYNJ1_HUMAN (162-550): 1.33e-14: 79.5: 10.72		AP2A1_HUMAN (1-939): 0: 833: 78.67
+	Rn
		88753 AMPH_RAT (91-588): 1.14e-11: 69.5: 16.51		D3ZUY8_RAT (1-939): 0: 836: 81.25
+	Hs
		827733 AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97		AP2B1_HUMAN (36-934): 0: 629: 16.82
+	Hs
		203219 SYNJ1_HUMAN (162-550): 1.33e-14: 79.5: 10.72		AP2B1_HUMAN (36-934): 0: 629: 16.82
+	Hs
		827743 AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97		AP1B1_HUMAN (36-934): 0: 625: 17.55
+	Mm
		1186720 AMPH_MOUSE (43-588): 1.62e-14: 78.8: 17.03		AP2B1_MOUSE (36-934): 0: 628: 16.72
+	Hs
		203223 SYNJ1_HUMAN (162-550): 1.33e-14: 79.5: 10.72		AP1B1_HUMAN (36-934): 0: 625: 17.55
+	Rn
		139975 AMPH_RAT (91-588): 1.14e-11: 69.5: 16.51		AP2B1_RAT (36-934): 0: 629: 16.82
+	Hs
		212606 AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97		AP1G1_HUMAN (1-824): 0: 599: 24.91
+	Sc
		764159 RV167_YEAST (16-383): 3.27e-41: 157: 14.43		AP3D_YEAST (51-604): 1.66e-18: 93.2: 21.24
+	Sc
		758554 SEC31_YEAST (161-536): 7.83e-09: 61: 11.05		AP3D_YEAST (51-604): 1.66e-18: 93.2: 21.24