Interactor 1: P85B (O08908)
Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta)
Gene: Pik3r2

Interactor 2: CRK (Q64010)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 20697350
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PI3K_P85_iSH2~SH2, SH2~SH3_1, SH2~SH3_2
Common GO terms GO:0001784 - phosphotyrosine residue binding
GO:0030971 - receptor tyrosine kinase binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 722
Mm

1 304
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Last updated: 15 Jul 2024