Protein: HXB9
Homeobox protein Hox-B9 (Homeobox protein Hox-2.5) (Homeobox protein Hox-2E)

Gene: HXB9, HOXB9
Organism: Homo sapiens
Interactions: 125
UniProt ID: P17482

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604796

HXA1
Homeobox protein Hox-A1

2

18

High-throughput

0.783

High

604854

MDFI
MyoD family inhibitor

4

1

High-throughput

0.703

High

604783

TAL1
T-cell acute lymphocytic leukemia protein 1

1

20

High-throughput

0.698

High

604818

TCAL1
Transcription elongation factor A protein-like 1

3

1

High-throughput

0.667

High

604822

MK14
Mitogen-activated protein kinase 14

3

8

High-throughput

0.667

High

604856

HOP
Homeodomain-only protein

1

0

High-throughput

0.663

High

604882

ARI1
E3 ubiquitin-protein ligase ARIH1

2

5

High-throughput

0.628

High

604784

SAT1
Diamine acetyltransferase 1

3

2

High-throughput

0.628

High

604834

CERS6
Ceramide synthase 6

1

4

High-throughput

0.618

High

209949

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.618

High

224937

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.618

High

604791

TLX1
T-cell leukemia homeobox protein 1

1

17

High-throughput

0.618

High

604873

VSX1
Visual system homeobox 1

1

19

High-throughput

0.618

High

604842

PNMA1
Paraneoplastic antigen Ma1

3

1

High-throughput

0.616

High

604878

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

20

High-throughput

0.616

High

239920

SOX15
Transcription factor SOX-15

2

20

High-throughput

0.614

High

180225

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

1

High-throughput

0.606

High

217053

MS18B
Protein Mis18-beta

2

2

High-throughput

0.606

High

571864

TRI27
Zinc finger protein RFP

2

10

High-throughput

0.606

High

604827

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

1

High-throughput

0.606

High

604828

FHL5
Four and a half LIM domains protein 5

2

7

High-throughput

0.606

High

604833

TEN4
Teneurin-4

2

4

High-throughput

0.606

High

604844

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

5

High-throughput

0.606

High

604852

PFD5
Prefoldin subunit 5

2

1

High-throughput

0.606

High

604875

SMBT1
Scm-like with four MBT domains protein 1

2

3

High-throughput

0.606

High

604859

LZTS2
Leucine zipper putative tumor suppressor 2

3

2

High-throughput

0.604

High

604812

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

604821

HSPB2
Heat shock protein beta-2

2

0

High-throughput

0.580

High

604847

EXOS8
Exosome complex component RRP43

2

0

High-throughput

0.580

High

604845

KAT2B
Histone acetyltransferase KAT2B

1

2

Small-scale

0.578

High

399540

VTNC
Vitronectin

2

1

High-throughput

0.574

High

604849

SAHH3
Adenosylhomocysteinase 3

2

7

High-throughput

0.574

High

604876

NAGK
N-acetyl-D-glucosamine kinase

2

3

High-throughput

0.574

High

604881

WASF3
Actin-binding protein WASF3

2

11

High-throughput

0.574

High

604815

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

2

High-throughput

0.573

High

604820

TRIP6
Thyroid receptor-interacting protein 6

1

6

High-throughput

0.573

High

604848

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

8

Small-scale

0.561

High

429260

JUN
Transcription factor Jun

1

11

High-throughput

0.554

High

65014

GG6L9
Golgin subfamily A member 6-like protein 9

2

5

High-throughput

0.553

High

70109

CRTP1
Cysteine-rich tail protein 1

2

5

High-throughput

0.553

High

300296

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.553

High

604798

KR122
Keratin-associated protein 12-2

2

20

High-throughput

0.553

High

604799

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.553

High

604810

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

604823

KRA62
Keratin-associated protein 6-2

2

3

High-throughput

0.553

High

604826

PKHG4
Puratrophin-1

2

1

High-throughput

0.553

High

604829

TENS2
Tensin-2

2

4

High-throughput

0.553

High

604830

K1C40
Keratin, type I cytoskeletal 40

2

20

High-throughput

0.553

High

604831

KRA57
Keratin-associated protein 5-7

2

20

High-throughput

0.553

High

604837

K1C27
Keratin, type I cytoskeletal 27

2

12

High-throughput

0.553

High

604838

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

604861

CAR10
Caspase recruitment domain-containing protein 10

2

3

High-throughput

0.553

High

604864

KRA42
Keratin-associated protein 4-2

2

20

High-throughput

0.553

High

604865

KRA32
Keratin-associated protein 3-2

2

3

High-throughput

0.553

High

604866

KRA31
Keratin-associated protein 3-1

2

3

High-throughput

0.553

High

604868

KRA15
Keratin-associated protein 1-5

2

20

High-throughput

0.553

High

604846

RBPMS
RNA-binding protein with multiple splicing

1

3

High-throughput

0.541

High

604871

ZN408
Zinc finger protein 408

1

4

High-throughput

0.541

High

604880

ING4
Inhibitor of growth protein 4

1

2

High-throughput

0.541

High

133080

FOXE1
Forkhead box protein E1

1

20

High-throughput

0.536

High

221915

FOXS1
Forkhead box protein S1

1

20

High-throughput

0.536

High

486932

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.536

High

562550

RINI
Ribonuclease inhibitor

1

5

High-throughput

0.536

High

604785

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.536

High

604786

S100P
Protein S100-P

1

20

High-throughput

0.536

High

604797

FOXA1
Hepatocyte nuclear factor 3-alpha

1

20

High-throughput

0.536

High

604806

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.536

High

604807

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

5

High-throughput

0.536

High

604808

SUH
Recombining binding protein suppressor of hairless

1

9

High-throughput

0.536

High

604813

FOXF1
Forkhead box protein F1

1

20

High-throughput

0.536

High

604814

FOXC1
Forkhead box protein C1

1

20

High-throughput

0.536

High

604817

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

1

High-throughput

0.536

High

604855

FOXC2
Forkhead box protein C2

1

20

High-throughput

0.536

High

604832

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.529

High

604801

BTG1
Protein BTG1

1

2

Small-scale

0.527

High

604804

BTG2
Protein BTG2

1

2

Small-scale

0.527

High

604787

KRA59
Keratin-associated protein 5-9

1

20

High-throughput

0.523

High

604800

KR109
Keratin-associated protein 10-9

1

20

High-throughput

0.523

High

604811

GOGA2
Golgin subfamily A member 2

1

5

High-throughput

0.523

High

604858

MBB1A
Myb-binding protein 1A

1

0

High-throughput

0.518

High

604862

SPZ1
Spermatogenic leucine zipper protein 1

1

0

High-throughput

0.518

High

552910

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

604841

EIF1A
Probable RNA-binding protein EIF1AD

1

0

High-throughput

0.513

High

604843

CBP
CREB-binding protein

1

15

Small-scale

0.501

High

604857

KR412
Keratin-associated protein 4-12

1

20

High-throughput

0.494

High

229947

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

7

High-throughput

0.489

High

604789

S10A2
Protein S100-A2

1

20

High-throughput

0.489

High

604790

CD6
T-cell differentiation antigen CD6

1

2

High-throughput

0.489

High

604835

MTSS2
Protein MTSS 2

1

3

High-throughput

0.489

High

142823

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

473773

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

604788

TEAD1
Transcriptional enhancer factor TEF-1

1

5

High-throughput

0.479

High

604792

COIL
Coilin

1

2

High-throughput

0.479

High

604793

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

604794

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

4

High-throughput

0.479

High

604795

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

604802

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

604803

H31
Histone H3.1

1

3

High-throughput

0.479

High

604805

H33
Histone H3.3

1

3

High-throughput

0.479

High

604809

PAX8
Paired box protein Pax-8

1

20

High-throughput

0.479

High

604816

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

604819

TEAD2
Transcriptional enhancer factor TEF-4

1

5

High-throughput

0.479

High

604850

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

604853

FEV
Protein FEV

1

10

High-throughput

0.479

High

604869

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

604870

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

604877

FOXD3
Forkhead box protein D3

1

20

High-throughput

0.479

High

516961

NT2NC
Notch homolog 2 N-terminal-like protein C

1

12

High-throughput

0.470

High

604824

KRA63
Keratin-associated protein 6-3

1

4

High-throughput

0.470

High

604867

KRA24
Keratin-associated protein 2-4

1

20

High-throughput

0.470

High

604839

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

604860

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

344085

PTBP3
Polypyrimidine tract-binding protein 3

1

3

High-throughput

0.445

High

604840

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.445

High

476

NBPFJ
NBPF family member NBPF19

1

4

High-throughput

0.439

High

505301

KRA23
Keratin-associated protein 2-3

1

20

High-throughput

0.439

High

604836

NT2NA
Notch homolog 2 N-terminal-like protein A

1

12

High-throughput

0.439

High

604851

CP2S1
Cytochrome P450 2S1

2

0

High-throughput

0.328

High

604874

CKLF
Chemokine-like factor

2

0

High-throughput

0.324

High

50317

F168B
Myelin-associated neurite-outgrowth inhibitor

2

0

High-throughput

0.316

High

604825

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.316

High

604863

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.316

High

604872

BPIA1
BPI fold-containing family A member 1

2

0

High-throughput

0.316

High

604879

PHTF1
Protein PHTF1

1

0

High-throughput

0.282

High

345340

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025