HitPredict

Interactor 1: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: SIN3A (Q60520)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.751

The method score is based on:

Property Details
Experiments 10688671, 16103876, 10409740, 21454521, 21448134, 16109738, 11302704, 20404188, 19424149, 24240174
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
and 15 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 482
Mm

1 1274
+ Mm
+ Hs
+ Hs
+ Mm
+ Sp
+ Ce
+ Ce
+ At
+ At
+ Dm
+ Sc
+ Dm
+ Hs
+ Hs
+ Sp
+ Sc
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024