Interactor 1: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: SIN3B (Q62141)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.676

The method score is based on:

Property Details
Experiments 16103876, 11302704, 10409740, 21041482
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 482
Mm

1 1098
+ Hs
+ Hs
+ Sp
+ At
+ At
+ Dm
+ Dm
+ Mm
+ Hs
+ Hs
+ Mm
+ Ce
+ Ce
+ Sc
+ Sp
+ Sc
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024