Protein: NECT3
Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113)

Gene: NECT3, NECTIN3
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q9NQS3

Gene Ontology (top 5):
GO:0002089 - lens morphogenesis in camera-type eye
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005912 - adherens junction
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1144346

NECT1
Nectin-1

6

17

Small-scale

0.953

High

1366784

NECT2
Nectin-2

6

17

Small-scale

0.952

High

635007

MAK
Serine/threonine-protein kinase MAK

3

2

High-throughput

0.861

High

1413105

INP5K
Inositol polyphosphate 5-phosphatase K

3

1

High-throughput

0.861

High

1447205

NECT3
Nectin-3

2

19

Small-scale

0.790

High

580839

PVR
Poliovirus receptor

2

17

Small-scale

0.778

High

1277420

NT2NA
Notch homolog 2 N-terminal-like protein A

3

20

High-throughput

0.770

High

374217

RASN
GTPase NRas

2

20

High-throughput

0.754

High

375987

RASK
GTPase KRas

2

20

High-throughput

0.754

High

1193164

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

4

Small-scale

0.724

High

127399

LEG8
Galectin-8

2

18

High-throughput

0.705

High

1052180

COEA1
Collagen alpha-1(XIV) chain

2

18

High-throughput

0.705

High

480904

LEG1
Galectin-1

1

18

High-throughput

0.691

High

1180968

HFE
Hereditary hemochromatosis protein

1

2

High-throughput

0.691

High

1447208

BTNL2
Butyrophilin-like protein 2

1

19

High-throughput

0.691

High

1447211

CLC4A
C-type lectin domain family 4 member A

1

10

High-throughput

0.691

High

1447213

PCDB3
Protocadherin beta-3

1

2

High-throughput

0.691

High

936456

AFAD
Afadin

3

20

Small-scale

0.679

High

1086120

ASPH
Aspartyl/asparaginyl beta-hydroxylase

3

0

High-throughput

0.638

High

126819

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

363899

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

411070

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.618

High

466480

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

581310

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

601462

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

774648

BASI
Basigin

1

18

High-throughput

0.618

High

845818

MUC18
Cell surface glycoprotein MUC18

1

19

High-throughput

0.618

High

910214

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

945106

RAB25
Ras-related protein Rab-25

1

9

High-throughput

0.618

High

953695

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

955637

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

962525

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

962838

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

978329

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

988739

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1015824

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1151891

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1271008

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1366891

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1396636

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1433522

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1438172

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1447210

ALK
ALK tyrosine kinase receptor

1

18

High-throughput

0.618

High

950696

KR108
Keratin-associated protein 10-8

3

20

High-throughput

0.616

High

1447206

PICK1
PRKCA-binding protein

2

5

Small-scale

0.614

High

1447209

FBX2
F-box only protein 2

3

11

High-throughput

0.609

High

1350083

SPP2B
Signal peptide peptidase-like 2B

2

4

High-throughput

0.601

High

517119

NT2NC
Notch homolog 2 N-terminal-like protein C

1

20

High-throughput

0.594

High

262316

SCN2B
Sodium channel regulatory subunit beta-2

1

18

High-throughput

0.575

High

641982

CD9
CD9 antigen

1

12

High-throughput

0.575

High

948940

CD81
CD81 antigen

1

12

High-throughput

0.575

High

303194

RGS20
Regulator of G-protein signaling 20

1

2

High-throughput

0.573

High

1353287

PARD3
Partitioning defective 3 homolog

1

20

Small-scale

0.561

High

70498

CRTP1
Cysteine-rich tail protein 1

2

3

High-throughput

0.553

High

685960

KRA59
Keratin-associated protein 5-9

2

20

High-throughput

0.553

High

733223

OTX1
Homeobox protein OTX1

2

1

High-throughput

0.553

High

1059748

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

1235784

KR511
Keratin-associated protein 5-11

2

20

High-throughput

0.553

High

1307461

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

1419013

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

1419064

KRA41
Keratin-associated protein 4-1

2

20

High-throughput

0.553

High

347944

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.553

High

976586

RB11A
Ras-related protein Rab-11A

1

8

High-throughput

0.553

High

1382067

T106A
Transmembrane protein 106A

1

3

High-throughput

0.536

High

1433084

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.536

High

950413

KR107
Keratin-associated protein 10-7

1

20

High-throughput

0.523

High

950900

KR109
Keratin-associated protein 10-9

1

20

High-throughput

0.523

High

1419095

KRA42
Keratin-associated protein 4-2

1

20

High-throughput

0.523

High

637749

FLNA
Filamin-A

1

6

High-throughput

0.515

High

140453

SDCB1
Syntenin-1

1

16

Small-scale

0.501

High

1142679

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.489

High

1334576

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.489

High

1399396

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

2

High-throughput

0.489

High

1439353

SDF2L
Stromal cell-derived factor 2-like protein 1

1

4

High-throughput

0.489

High

218818

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.479

High

639

NBPFJ
NBPF family member NBPF19

1

5

High-throughput

0.439

High

950014

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.439

High

1419055

KR411
Keratin-associated protein 4-11

1

20

High-throughput

0.439

High

1400338

FMNL2
Formin-like protein 2

1

2

High-throughput

0.437

High

1404637

SDF2
Stromal cell-derived factor 2

1

4

High-throughput

0.437

High

1447207

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.426

High

1154261

NPTX1
Neuronal pentraxin-1

3

0

High-throughput

0.347

High

1294935

ERO1B
ERO1-like protein beta

2

0

High-throughput

0.318

High

1234623

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.279

Low

1447212

FBX7
F-box only protein 7

1

0

High-throughput

0.279

Low

256391

RT14
Small ribosomal subunit protein uS14m

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025