HitPredict

Interactor 1: SCN2A (Q99250)
Sodium channel protein type 2 subunit alpha (HBSC II) (Sodium channel protein brain II subunit alpha) (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2)
Gene: SCN2A

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36950384
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007399 - nervous system development
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2005 Hs			1 599
+	Hs
		135321 SCN2A_HUMAN (1-2005): 0: 2119: 100.00		IF2B3_HUMAN (2-599): 4.98e-140: 420: 62.19
+	Hs
		1403984 SCN2A_HUMAN (1-2005): 0: 2119: 100.00		IF2B1_HUMAN (2-599): 6.45e-136: 410: 63.89
+	Hs
		550427 SCN2A_HUMAN (1-2005): 0: 2119: 100.00		PABP1_HUMAN (2-444): 5.64e-43: 165: 14.58
+	Hs
		1119411 CAC1C_HUMAN (24-275): 2.31e-20: 101: 17.52		IF2B2_HUMAN (1-599): 1.75e-152: 453: 100.00
+	Hs
		135206 CAC1C_HUMAN (24-275): 2.31e-20: 101: 17.52		IF2B3_HUMAN (2-599): 4.98e-140: 420: 62.19
+	Hs
		1119338 CAC1C_HUMAN (24-275): 2.31e-20: 101: 17.52		IF2B1_HUMAN (2-599): 6.45e-136: 410: 63.89
+	Hs
		550277 CAC1C_HUMAN (24-275): 2.31e-20: 101: 17.52		PABP1_HUMAN (2-444): 5.64e-43: 165: 14.58
+	Hs
		965670 CAC1C_HUMAN (24-275): 2.31e-20: 101: 17.52		HNRPK_HUMAN (390-596): 9.53e-21: 97.3: 17.83
+	Hs
		1119133 CAC1C_HUMAN (24-275): 2.31e-20: 101: 17.52		PCBP1_HUMAN (420-530): 6.93e-11: 66.1: 25.23
+	Hs
		1119134 CAC1C_HUMAN (24-275): 2.31e-20: 101: 17.52		PCBP2_HUMAN (500-581): 3.56e-09: 61: 19.51