Interactor 1: CAR10 (Q9BWT7)
Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3)
Gene: CARD10

Interactor 2: CARD9 (Q9H257)
Caspase recruitment domain-containing protein 9 (hCARD9)
Gene: CARD9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.836

The method score is based on:

Property Details
Experiments 32296183, unassigned1304, unassigned3799
Identification Methods two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~CARD
Common GO terms GO:0005737 - cytoplasm
GO:0032449 - CBM complex
GO:0042981 - regulation of apoptotic process
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0050776 - regulation of immune response
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1032
Hs

1 536
+ Hs
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 11Aug2025