HitPredict

Interactor 1: SED5 (O13644)
Integral membrane protein sed5
Gene: SED5

Interactor 2: SLY1 (O74534)
Protein sly1
Gene: SLY1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	26771498
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SNARE~Sec1, Sec1~Syntaxin-5_N
Common GO terms	GO:0000139 - Golgi membrane GO:0006886 - intracellular protein transport GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 309 Sp			1 639
+	At
		1338394 SYP32_ARATH (2-308): 6.2e-60: 196: 33.83		SLY1_ARATH (8-638): 8.46e-176: 515: 34.32
+	Dm
		1096638 STX5_DROME (1-294): 1.51e-59: 198: 38.51		SLY1_DROME (10-638): 2.11e-172: 507: 35.02
+	Mm
		192851 STX1A_MOUSE (4-306): 6.52e-50: 168: 16.07		STXB2_MOUSE (27-639): 2.67e-174: 510: 18.79
+	Hs
		1027531 STX5_HUMAN (1-293): 4.79e-52: 176: 39.12		SCFD1_HUMAN (11-638): 2.91e-170: 501: 34.91
+	Rn
		699178 STX1A_RAT (4-306): 7.58e-50: 168: 16.07		STXB2_RAT (22-639): 1.72e-171: 503: 19.43
+	Hs
		699262 STX2_HUMAN (4-308): 1.82e-48: 165: 13.68		STXB2_HUMAN (27-639): 2.16e-172: 505: 19.27
+	Dm
		1096639 STX1A_DROME (3-304): 3.8e-47: 162: 14.43		SLY1_DROME (10-638): 2.11e-172: 507: 35.02
+	Rn
		901848 STX5_RAT (1-293): 5.77e-57: 189: 39.46		STXB1_RAT (46-639): 2.32e-156: 464: 18.46
+	Hs
		901778 STX5_HUMAN (1-293): 4.79e-52: 176: 39.12		STXB1_HUMAN (46-639): 2.32e-156: 464: 18.46
+	Ce
		183451 STX1A_CAEEL (3-308): 8.76e-50: 168: 13.68		UNC18_CAEEL (19-639): 3.24e-158: 469: 19.40
+	Dm
		991124 STX1A_DROME (3-304): 3.8e-47: 162: 14.43		ROP_DROME (39-639): 1.65e-159: 472: 18.12
+	Mm
		139528 STX1A_MOUSE (4-306): 6.52e-50: 168: 16.07		STXB1_MOUSE (46-639): 2.32e-156: 464: 18.46
+	Bt
		699167 STX1A_BOVIN (4-306): 8.53e-50: 168: 15.41		STXB1_BOVIN (46-639): 2.32e-156: 464: 18.46
+	Rn
		699173 STX1A_RAT (4-306): 7.58e-50: 168: 16.07		STXB1_RAT (46-639): 2.32e-156: 464: 18.46
+	Mm
		139543 STX1B_MOUSE (4-306): 1.04e-48: 165: 13.77		STXB1_MOUSE (46-639): 2.32e-156: 464: 18.46
+	Hs
		699253 STX2_HUMAN (4-308): 1.82e-48: 165: 13.68		STXB1_HUMAN (46-639): 2.32e-156: 464: 18.46
+	Rn
		898824 STX1B_RAT (4-306): 1.04e-48: 165: 13.77		STXB1_RAT (46-639): 2.32e-156: 464: 18.46
+	Hs
		898829 STX1B_HUMAN (4-306): 1.04e-48: 165: 13.77		STXB1_HUMAN (46-639): 2.32e-156: 464: 18.46
+	Hs
		901790 STX1A_HUMAN (4-306): 9.37e-49: 165: 15.74		STXB1_HUMAN (46-639): 2.32e-156: 464: 18.46
+	Hs
		119613 STX2_HUMAN (4-308): 1.82e-48: 165: 13.68		STXB3_HUMAN (43-639): 1.12e-151: 452: 18.06