HitPredict

Interactor 1: CCN1 (O00622)
CCN family member 1 (Cellular communication network factor 1) (Cysteine-rich angiogenic inducer 61) (Insulin-like growth factor-binding protein 10) (IBP-10) (IGF-binding protein 10) (IGFBP-10) (Protein CYR61) (Protein GIG1)
Gene: CCN1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction GO:0007229 - integrin-mediated signaling pathway GO:0030335 - positive regulation of cell migration
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 191
+	Hs
		142061 CCN1_HUMAN (1-381): 2.01e-162: 462: 100.00		RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73
+	Hs
		142058 CCN1_HUMAN (1-381): 2.01e-162: 462: 100.00		RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48
+	Hs
		142046 CCN1_HUMAN (1-381): 2.01e-162: 462: 100.00		RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41
+	Hs
		955291 Q6FHL8_HUMAN (9-370): 1.15e-136: 395: 46.58		CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00