Interactor 1: SMC5 (O13710)
Structural maintenance of chromosomes protein 5 (DNA repair protein spr18) (SMC partner of rad18)
Gene: SMC5

Interactor 2: SMC6 (P53692)
Structural maintenance of chromosomes protein 6 (DNA repair protein rad18)
Gene: SMC6

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 15601840, 26446992, 28134253, 16478984, 10747036, 15331764, 32546830, 12966087
Identification Methods pull down, affinity chromatography technology, two hybrid, x-ray crystallography, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SMC_N~SMC_N
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0016887 - ATP hydrolysis activity
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1076
Sp

1 1140
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Ce
+ Sc
+ Sc
+ Sc
+ Xl
+ Sp
+ Sp
+ Sp
+ Sp
+ Hs
+ Xl

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Last updated: 15 Jul 2024