Interactor 1: ERCC3 (O13768)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB (TFIIH subunit XPB) (EC 5.6.2.4) (DNA 3'-5' helicase/translocase XPB) (DNA repair helicase ptr8) (Poly(A)+ RNA transport protein 8) (RNA polymerase II transcription factor B subunit ercc3) (TFB subunit ercc3)
Gene: ptr8

Interactor 2: TFB2 (P87303)
General transcription and DNA repair factor IIH subunit tfb2 (TFIIH subunit tfb2) (RNA polymerase II transcription factor B subunit 2)
Gene: TFB2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 14534314, 15182371
Identification Methods affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ERCC3_RAD25_C~Tfb2, ERCC3_RAD25_C~Tfb2_C, Helicase_C_3~Tfb2
Common GO terms GO:0000112 - nucleotide-excision repair factor 3 complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005675 - transcription factor TFIIH holo complex
GO:0006367 - transcription initiation at RNA polymerase II promoter
GO:0016251 - RNA polymerase II general transcription initiation factor activity
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 804
Sp

1 447
+ Hs
+ Dm
+ Sc

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Last updated: 15 Jul 2024