HitPredict

Interactor 1: CUL1 (O13790)
Cullin-1 (Cul-1) (Cell division control 53 homolog)
Gene: CUL1

Interactor 2: CSN1 (O94308)
COP9 signalosome complex subunit 1 (CSN complex subunit 1) (SGN1)
Gene: CSN1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	12183637, 23535663
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 767 Sp			1 422
+	Hs
		1024157 CUL1_HUMAN (4-767): 0: 800: 40.66		CSN1_HUMAN (1-422): 3.84e-116: 349: 25.11
+	Hs
		1041600 CUL3_HUMAN (9-767): 0: 773: 28.55		PSMD6_HUMAN (8-398): 1.56e-124: 367: 19.29
+	Hs
		1024159 CUL3_HUMAN (9-767): 0: 773: 28.55		CSN1_HUMAN (1-422): 3.84e-116: 349: 25.11
+	Hs
		1024160 CUL4A_HUMAN (7-767): 0: 770: 28.79		CSN1_HUMAN (1-422): 3.84e-116: 349: 25.11
+	Hs
		1024161 CUL4B_HUMAN (7-767): 0: 753: 28.79		CSN1_HUMAN (1-422): 3.84e-116: 349: 25.11
+	Hs
		87385 CUL4B_HUMAN (7-767): 0: 753: 28.79		C9JFE4_HUMAN (1-422): 2.72e-116: 349: 25.56
+	Hs
		1024158 CUL2_HUMAN (14-767): 0: 732: 30.40		CSN1_HUMAN (1-422): 3.84e-116: 349: 25.11
+	At
		799476 CUL1_ARATH (13-767): 0: 730: 27.74		CSN1_ARATH (5-405): 7.16e-111: 334: 24.39
+	Mm
		897343 CUL1_MOUSE (4-767): 0: 803: 40.79		CSN2_MOUSE (3-369): 2.63e-75: 243: 13.02
+	Hs
		897242 CUL1_HUMAN (4-767): 0: 800: 40.66		CSN2_HUMAN (3-369): 2.63e-75: 243: 13.02
+	Sp
		142919 CUL1_SCHPO (1-767): 0: 829: 100.00		CSN2_SCHPO (2-391): 5.31e-62: 208: 13.18
+	Hs
		897244 CUL3_HUMAN (9-767): 0: 773: 28.55		CSN2_HUMAN (3-369): 2.63e-75: 243: 13.02
+	Hs
		897245 CUL4A_HUMAN (7-767): 0: 770: 28.79		CSN2_HUMAN (3-369): 2.63e-75: 243: 13.02
+	At
		1258869 CUL3A_ARATH (7-767): 0: 779: 29.34		CSN2_ARATH (3-366): 1.61e-66: 220: 13.37
+	Hs
		897246 CUL4B_HUMAN (7-767): 0: 753: 28.79		CSN2_HUMAN (3-369): 2.63e-75: 243: 13.02
+	Hs
		897243 CUL2_HUMAN (14-767): 0: 732: 30.40		CSN2_HUMAN (3-369): 2.63e-75: 243: 13.02
+	Ce
		1088888 CUL3_CAEEL (16-767): 0: 676: 27.25		CSN1_CAEEL (2-406): 1.9e-89: 284: 19.65
+	Sp
		292919 CUL3_SCHPO (16-767): 0: 617: 25.25		CSN1_SCHPO (1-422): 4.78e-113: 339: 100.00
+	At
		1258866 CUL1_ARATH (13-767): 0: 730: 27.74		CSN2_ARATH (3-366): 1.61e-66: 220: 13.37
+	At
		1228139 CUL4_ARATH (9-767): 0: 708: 29.22		CSN3_ARATH (192-407): 6.73e-48: 171: 13.24