HitPredict

Interactor 1: GMF1 (O13808)
Actin-depolymerizing factor gmf1 (Glia maturation factor-like protein 1)
Gene: GMF1

Interactor 2: ARP2 (Q9UUJ1)
Actin-related protein 2 (Actin-like protein 2)
Gene: ARP2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20517925
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0030479 - actin cortical patch
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 141 Sp			1 390
+	At
		862533 ADF6_ARATH (3-141): 1.25e-50: 159: 18.57		ACT7_ARATH (2-386): 0: 565: 46.23
+	Hs
		894697 GMFB_HUMAN (1-140): 1.63e-42: 139: 35.00		ACTG_HUMAN (2-386): 0: 575: 46.49
+	Hs
		891650 GMFB_HUMAN (1-140): 1.63e-42: 139: 35.00		ACTB_HUMAN (2-386): 0: 574: 46.23
+	Hs
		618049 COF1_HUMAN (5-140): 4.57e-41: 136: 19.61		ACTG_HUMAN (2-386): 0: 575: 46.49
+	Mm
		578583 COF1_MOUSE (5-140): 3.06e-41: 136: 19.61		ACTB_MOUSE (2-386): 0: 574: 46.23
+	Hs
		618038 COF1_HUMAN (5-140): 4.57e-41: 136: 19.61		ACTB_HUMAN (2-386): 0: 574: 46.23
+	Hs
		618096 COF1_HUMAN (5-140): 4.57e-41: 136: 19.61		Q1KLZ0_HUMAN (2-386): 0: 574: 46.23
+	Rn
		799735 COF1_RAT (5-140): 4.83e-41: 136: 19.61		ACTB_RAT (2-386): 0: 574: 46.23
+	Hs
		618052 COF1_HUMAN (5-140): 4.57e-41: 136: 19.61		ACTC_HUMAN (2-386): 0: 569: 46.23
+	Hs
		618046 COF1_HUMAN (5-140): 4.57e-41: 136: 19.61		ACTA_HUMAN (2-386): 0: 568: 45.71
+	Hs
		618053 COF1_HUMAN (5-140): 4.57e-41: 136: 19.61		ACTS_HUMAN (2-386): 0: 568: 45.71
+	Sp
		501582 COFI_SCHPO (3-140): 4.18e-41: 135: 16.55		ACT_SCHPO (2-386): 0: 567: 45.46
+	Hs
		618050 COF1_HUMAN (5-140): 4.57e-41: 136: 19.61		ACTH_HUMAN (2-386): 0: 566: 45.71
+	Sc
		887656 COFI_YEAST (3-140): 2.04e-41: 136: 15.71		ACT_YEAST (2-386): 0: 566: 43.64
+	Hs
		618041 COF1_HUMAN (5-140): 4.57e-41: 136: 19.61		ARP2_HUMAN (6-386): 0: 537: 66.23
+	At
		477715 ADF4_ARATH (1-141): 4.66e-54: 168: 17.61		ACT1_ARATH (5-378): 9.55e-126: 369: 47.33
+	At
		1280858 ADF3_ARATH (1-141): 1.13e-52: 164: 18.31		ACT2_ARATH (5-378): 4.13e-126: 370: 47.86
+	At
		477714 ADF6_ARATH (3-141): 1.25e-50: 159: 18.57		ACT1_ARATH (5-378): 9.55e-126: 369: 47.33
+	At
		477717 ADF6_ARATH (3-141): 1.25e-50: 159: 18.57		ACT3_ARATH (5-378): 9.55e-126: 369: 47.33
+	At
		862554 ADF6_ARATH (3-141): 1.25e-50: 159: 18.57		ACT12_ARATH (5-378): 1.96e-125: 368: 47.06