Interactor 1: PRP19 (O14011)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Complexed with cdc5 protein 8) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Interactor 2: PRP19 (O14011)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Complexed with cdc5 protein 8) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.829

The method score is based on:

Property Details
Experiments 26771498, 15601865, 21386897
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC4_WD40~ANAPC4_WD40, Prp19~Prp19
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
and 8 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 488
Sp

1 488
+ Hs
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+ Dm
+ Sc
+ Sp
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+ Mm
+ Hs
+ Hs
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+ Hs
+ Hs

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Last updated: 15 Jul 2024