HitPredict

Interactor 1: ACTN2 (Q9JI91)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2

Interactor 2: MYOZ2 (Q9JJW5)
Myozenin-2 (Calsarcin-1) (FATZ-related protein 2)
Gene: MYOZ2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29199018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Calsarcin~Spectrin
Common GO terms	GO:0030018 - Z disc GO:0045214 - sarcomere organization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 894 Mm			1 264
+	Hs
		555765 ACTN1_HUMAN (10-894): 0: 675: 80.00		MYOZ2_HUMAN (1-264): 2.1e-158: 442: 88.26
+	Hs
		773788 ACTN2_HUMAN (1-894): 0: 663: 99.22		MYOZ2_HUMAN (1-264): 2.1e-158: 442: 88.26
+	Hs
		224803 ACTN4_HUMAN (18-894): 0: 635: 78.23		MYOZ2_HUMAN (1-264): 2.1e-158: 442: 88.26
+	Hs
		555764 ACTN1_HUMAN (10-894): 0: 675: 80.00		MYOZ1_HUMAN (11-72): 1.54e-23: 98.7: 45.31
+	Hs
		773787 ACTN2_HUMAN (1-894): 0: 663: 99.22		MYOZ1_HUMAN (11-72): 1.54e-23: 98.7: 45.31
+	Hs
		1061560 ACTN3_HUMAN (25-894): 0: 649: 80.81		MYOZ1_HUMAN (11-72): 1.54e-23: 98.7: 45.31
+	Hs
		224802 ACTN4_HUMAN (18-894): 0: 635: 78.23		MYOZ1_HUMAN (11-72): 1.54e-23: 98.7: 45.31