Interactor 1: PRKN (Q9JK66)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN
Interactor 2: TRIB3 (Q9WTQ6)
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase)
Gene: TRIB3
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26224857 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~ubiquitin |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0010506 - regulation of autophagy GO:0019899 - enzyme binding and 4 others more... |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
