HitPredict

Interactor 1: PRP19 (O14011)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Complexed with cdc5 protein 8) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Interactor 2: PRP39 (O74970)
Pre-mRNA-processing factor 39
Gene: PRP39

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	21386897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Sp			1 612
+	Dm
		54163 Q7KLW9_DROME (1-487): 1.33e-106: 328: 24.71		SYF1_DROME (36-498): 9.55e-41: 160: 11.66
+	Hs
		1318164 PRP19_HUMAN (1-487): 1.28e-115: 351: 25.69		CRNL1_HUMAN (1-431): 2.59e-29: 125: 14.87
+	Sp
		144131 PRP19_SCHPO (1-488): 4.18e-104: 321: 96.95		SYF1_SCHPO (99-496): 7.67e-37: 148: 13.51
+	Hs
		1336498 PRP19_HUMAN (1-487): 1.28e-115: 351: 25.69		SYF1_HUMAN (12-539): 1.18e-26: 117: 11.31
+	Hs
		175300 PRP19_HUMAN (1-487): 1.28e-115: 351: 25.69		OGT1_HUMAN (1-243): 8.21e-18: 89.6: 11.74
+	Sc
		692300 PRP19_YEAST (1-451): 3.74e-64: 217: 19.75		PRP39_YEAST (23-586): 2.01e-58: 208: 19.57
+	Sc
		692350 PRP19_YEAST (1-451): 3.74e-64: 217: 19.75		PRP42_YEAST (21-465): 1.45e-57: 204: 19.16
+	Sc
		692376 PRP19_YEAST (1-451): 3.74e-64: 217: 19.75		CLF1_YEAST (1-554): 4.19e-53: 194: 12.77
+	Sp
		144108 PRP19_SCHPO (1-488): 4.18e-104: 321: 96.95		CLF1_SCHPO (1-266): 9.53e-14: 76.6: 13.55
+	Hs
		300229 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		PRP6_HUMAN (1-509): 1.79e-38: 153: 11.17
+	Hs
		1288293 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		CRNL1_HUMAN (1-431): 2.59e-29: 125: 14.87
+	Hs
		1288323 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		SYF1_HUMAN (12-539): 1.18e-26: 117: 11.31
+	Hs
		300095 WDR5_HUMAN (130-360): 3.43e-35: 135: 8.47		PRP6_HUMAN (1-509): 1.79e-38: 153: 11.17
+	Hs
		175177 TBL1R_HUMAN (257-487): 1.82e-48: 175: 16.60		OGT1_HUMAN (1-243): 8.21e-18: 89.6: 11.74
+	Hs
		1058000 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		RRP5_HUMAN (135-429): 2.79e-17: 88.5: 11.55
+	Hs
		1022304 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		CSTF3_HUMAN (1-244): 2.87e-11: 68.5: 12.89
+	Sp
		224207 TUP11_SCHPO (141-406): 8.81e-45: 167: 13.79		CYC8_SCHPO (1-229): 2.44e-10: 65.8: 10.21
+	Hs
		174768 WDR5_HUMAN (130-360): 3.43e-35: 135: 8.47		OGT1_HUMAN (1-243): 8.21e-18: 89.6: 11.74
+	Hs
		903230 WDR5_HUMAN (130-360): 3.43e-35: 135: 8.47		RRP5_HUMAN (135-429): 2.79e-17: 88.5: 11.55
+	Hs
		903236 WDR5_HUMAN (130-360): 3.43e-35: 135: 8.47		SART3_HUMAN (154-569): 1.37e-10: 66.5: 12.59