HitPredict

Interactor 1: UBX2 (O14048)
UBX domain-containing protein 2
Gene: UBX2

Interactor 2: CDC48 (Q9P3A7)
Cell division cycle protein 48 (EC 3.6.4.6) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	15120077, 28821619
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CDC48_2~UBX, CDC48_N~UBX
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Sp			1 815
+	At
		870959 PUX7_ARATH (2-422): 3.71e-121: 362: 25.97		CD48A_ARATH (17-808): 0: 718: 67.38
+	Hs
		299344 UBXN7_HUMAN (2-424): 3.88e-120: 360: 23.48		TERA_HUMAN (26-814): 0: 719: 70.16
+	At
		67566 A8MRM0_ARATH (2-422): 2.99e-118: 354: 25.05		CD48A_ARATH (17-808): 0: 718: 67.38
+	Hs
		875209 FAF2_HUMAN (1-424): 5.34e-103: 314: 15.61		TERA_HUMAN (26-814): 0: 719: 70.16
+	Dm
		1180101 Q7K4I5_DROME (2-423): 1.88e-87: 276: 22.22		TERA_DROME (26-815): 0: 728: 68.59
+	Sc
		636759 UBX5_YEAST (5-425): 3.65e-91: 286: 28.14		CDC48_YEAST (22-815): 0: 710: 74.27
+	Mm
		872336 FAF1_MOUSE (101-424): 1.25e-82: 268: 12.96		TERA_MOUSE (26-814): 0: 719: 70.16
+	Hs
		875432 FAF1_HUMAN (101-424): 9.89e-83: 268: 12.68		TERA_HUMAN (26-814): 0: 719: 70.16
+	Sp
		251597 UCP10_SCHPO (5-403): 1.3e-67: 222: 14.04		CDC48_SCHPO (1-815): 0: 756: 100.00
+	Sc
		636779 UBX3_YEAST (120-420): 6.44e-62: 208: 12.58		CDC48_YEAST (22-815): 0: 710: 74.27
+	Ce
		110126 UBXN3_CAEEL (127-411): 1.46e-42: 160: 14.46		TERA1_CAEEL (19-812): 0: 703: 66.63
+	Ce
		110127 UBXN3_CAEEL (127-411): 1.46e-42: 160: 14.46		TERA2_CAEEL (19-798): 0: 699: 65.61
+	Hs
		116676 UBXN8_HUMAN (299-423): 2.23e-25: 106: 14.96		TERA_HUMAN (26-814): 0: 719: 70.16
+	Rn
		193676 NSF1C_RAT (1-423): 1.38e-15: 79.9: 14.15		TERA_RAT (26-814): 0: 719: 70.16
+	Ce
		873000 UBXN5_CAEEL (296-404): 6.25e-20: 88.4: 17.43		TERA1_CAEEL (19-812): 0: 703: 66.63
+	Ce
		873012 UBXN5_CAEEL (296-404): 6.25e-20: 88.4: 17.43		TERA2_CAEEL (19-798): 0: 699: 65.61
+	Rn
		472980 UBX2B_RAT (264-427): 2.47e-09: 60.2: 20.00		TERA_RAT (26-814): 0: 719: 70.16
+	Sc
		636608 UBX7_YEAST (156-424): 2.72e-11: 67.2: 14.19		CDC48_YEAST (22-815): 0: 710: 74.27
+	Ce
		712421 UBXN4_CAEEL (267-427): 5e-11: 66.4: 13.17		TERA1_CAEEL (19-812): 0: 703: 66.63
+	Ce
		712422 UBXN4_CAEEL (267-427): 5e-11: 66.4: 13.17		TERA2_CAEEL (19-798): 0: 699: 65.61